In silico exploration of Red Sea Bacillus genomes for natural product biosynthetic gene clusters.

ABSTRACT:

Background

The increasing spectrum of multidrug-resistant bacteria is a major global public health concern, necessitating discovery of novel antimicrobial agents. Here, members of the genus Bacillus are investigated as a potentially attractive source of novel antibiotics due to their broad spectrum of antimicrobial activities. We specifically focus on a computational analysis of the distinctive biosynthetic potential of Bacillus paralicheniformis strains isolated from the Red Sea, an ecosystem exposed to adverse, highly saline and hot conditions.

Results

We report the complete circular and annotated genomes of two Red Sea strains, B. paralicheniformis Bac48 isolated from mangrove mud and B. paralicheniformis Bac84 isolated from microbial mat collected from Rabigh Harbor Lago

SUBMITTER: Othoum G 

PROVIDER: S-EPMC5964695 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature