Education, Occupational Complexity, and Incident Dementia: A COSMIC Collaborative Cohort Study.

ABSTRACT:

Background

Education and occupational complexity are main sources of mental engagement during early life and adulthood respectively, but research findings are not conclusive regarding protective effects of these factors against late-life dementia.

Objective

This project aimed to examine the unique contributions of education and occupational complexity to incident dementia, and to assess the mediating effects of occupational complexity on the association between education and dementia across diverse cohorts.

Method

We used data from 10,195 participants (median baseline age = 74.1, range = 58∼103), representing 9 international datasets from 6 countries over 4 continents. Using a coordinated analysis approach, the accelerated failure time model was applied to each datase

SUBMITTER: Hyun J 

PROVIDER: S-EPMC8748312 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature