Association Between White Matter Hyperintensities and Chronic Kidney Disease: A Systematic Review and Meta-Analysis.

ABSTRACT:

Objectives

Previous studies of the associations between white matter hyperintensities (WMH) and chronic kidney disease (CKD) were still conflicting; therefore, our study aimed to conduct a systematic review of all of the available research on this topic and a meta-analysis of the association between WMH and CKD among observational studies.

Setting and design

Systematic review and meta-analysis.

Outcome measures

Severity of WMH.

Methods and participants

All relevant studies in public databases were examined until 15 November 2020. Two independent reviewers assessed all the included studies using the Cross-Sectional/Prevalence Study Quality (CSSQ) scale, and then literature review and meta-analyses were undertaken.

Results

We pooled the odds ratio (OR) for

SUBMITTER: Wei CS 

PROVIDER: S-EPMC9112853 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature