RF coil design for accurate parallel imaging on ¹³ C MRSI using ²³ Na sensitivity profiles.

ABSTRACT:

Purpose

To develop a coil-based method to obtain accurate sensitivity profiles in ¹³ C MRI at 3T from the endogenous ²³ Na. An eight-channel array is designed for ¹³ C MR acquisitions. As application examples, the array is used for two-fold accelerated acquisitions of both hyperpolarized ¹³ C metabolic imaging of pig kidneys and the human brain.

Methods

A flexible coil array was tuned optimally for ¹³ C at 3T (32.1 MHz), with the coil coupling coefficients matched to be nearly identical at the resonance frequency of ²³ Na (33.8 MHz). This is done by enforcing a high decoupling (obtained through highly mismatched preamplifiers) and adjusting the coupling frequency response. The SNR performance is compared to re

SUBMITTER: Sanchez-Heredia JD 

PROVIDER: S-EPMC9328386 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature