Pathological predictors of ¹⁸ F-DCFPyL prostate-specific membrane antigen-positive recurrence after radical prostatectomy.

ABSTRACT:

Objectives

To assess the correlation of pathological radical prostatectomy (RP) specimen features and prostate-specific antigen (PSA) characteristics to imaging findings on subsequent ¹⁸ F-DCFPyL positron emission tomography/computed tomography (PET/CT) in patients with biochemical failure (BF).

Patients and methods

Retrospective analysis of combined ¹⁸ F-DCFPyL PET/CT database of patients from centres in Australia and New Zealand was performed. A total of 205 patients presenting with BF after RP were included in this study. Imaging findings on ¹⁸ F-DCFPyL PET/CT were recorded and correlated with the PSA characteristics at BF and pathological features of the original tumour.

Results

Of the 205 patients, 120 (58.5%) had evidence of abno

SUBMITTER: Perry E 

PROVIDER: S-EPMC9540526 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature