Shortened duration whole body ¹⁸F-FDG PET Patlak imaging on the Biograph Vision Quadra PET/CT using a population-averaged input function.

ABSTRACT:

Background

Excellent performance characteristics of the Vision Quadra PET/CT, e.g. a substantial increase in sensitivity, allow for precise measurements of image-derived input functions (IDIF) and tissue time activity curves. Previously we have proposed a method for a reduced 30 min (as opposed to 60 min) whole body ¹⁸F-FDG Patlak PET imaging procedure using a previously published population-averaged input function (PIF) scaled to IDIF values at 30-60 min post-injection (p.i.). The aim of the present study was to apply this method using the Vision Quadra PET/CT, including the use of a PIF to allow for shortened scan durations.

Methods

Twelve patients with suspected lung malignancy were included and received a weight-based injection of ¹⁸F-FDG. Patients

SUBMITTER: van Sluis J 

PROVIDER: S-EPMC9618000 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature