Functional impact of multi-omic interactions in breast cancer subtypes.
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ABSTRACT:
SUBMITTER: Ochoa S
PROVIDER: S-EPMC9850112 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
Publications
Functional impact of multi-omic interactions in breast cancer subtypes.
Ochoa Soledad S Hernández-Lemus Enrique E
Frontiers in genetics 20230105
Multi-omic approaches are expected to deliver a broader molecular view of cancer. However, the promised mechanistic explanations have not quite settled yet. Here, we propose a theoretical and computational analysis framework to semi-automatically produce network models of the regulatory constraints influencing a biological function. This way, we identified functions significantly enriched on the analyzed omics and described associated features, for each of the four breast cancer molecular subtyp ...[more]
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