Coulibaly2019 - Interleukin-15 Signaling in HIF-1a Regulation in Natural Killer Cells

ABSTRACT:

This is a mathematical model comprised of non-linear ordinary differential equations describing the dynamic relationship between hypoxia-inducible factor-1 alpha (HIF-1a) mRNA, HIF-1a protein, and interleukin-15-mediated upstream signalling events in natural killer cells from human blood. Regulatory expressions are also included for mammalian target of rapamycin (mTOR), nuclear factor-kappa beta, and signal transducer and activator of transcription 3 (STAT3).

ORGANISM(S): Homo sapiens

SUBMITTER: Lucian Smith 

PROVIDER: MODEL1911180002 | biostudies-other |

SECONDARY ACCESSION(S): 31681292

REPOSITORIES: biostudies-other