Dataset Information
Cerebrospinal fluid (CSF) proteome, Zhang et al.
Ontology highlight
ABSTRACT:
INSTRUMENT(S): LCQ Deca, instrument model, LTQ
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cerebrospinal Fluid
SUBMITTER: 
Jing Zhang
PROVIDER: PRD000019 | Pride | 2007-02-14
REPOSITORIES: Pride
Publications
Detection of biomarkers with a multiplex quantitative proteomic platform in cerebrospinal fluid of patients with neurodegenerative disorders.
Journal of Alzheimer's disease : JAD 20060801 3
Biomarkers are needed to assist in the diagnosis and medical management of various neurodegenerative disorders, including Alzheimer's disease (AD), Parkinson's disease (PD), and dementia with Lewy body (DLB). We have employed a multiplex quantitative proteomics method, iTRAQ (isobaric Tagging for Relative and Absolute protein Quantification), in conjunction with multidimensional chromatography, followed by tandem mass spectrometry (MS/MS), to simultaneously measure relative changes in the proteo ...[more]
