Ontology highlight
ABSTRACT:
INSTRUMENT(S): ThermoFinnigan LTQ, ThermoFinnigan LCQ Deca XP
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cerebrospinal Fluid
SUBMITTER:
Jing Zhang
LAB HEAD: Jing Zhang
PROVIDER: PRD000019 | Pride | 2007-02-14
REPOSITORIES: Pride
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Journal of Alzheimer's disease : JAD 20060801 3
Biomarkers are needed to assist in the diagnosis and medical management of various neurodegenerative disorders, including Alzheimer's disease (AD), Parkinson's disease (PD), and dementia with Lewy body (DLB). We have employed a multiplex quantitative proteomics method, iTRAQ (isobaric Tagging for Relative and Absolute protein Quantification), in conjunction with multidimensional chromatography, followed by tandem mass spectrometry (MS/MS), to simultaneously measure relative changes in the proteo ...[more]