Analysis of Plasmodium sporozoites collected from mosquito saliva

ABSTRACT: Plasmodium sporozoites are injected, in addition to saliva, into animal hosts when a female Anopheles mosquito takes a blood meal. The molecular components of saliva that interact with Plasmodium during this process are poorly characterized. Here we collected Plasmodium sporozoites directly from salivating Anopheles mosquitoes and looked for the presence of vector proteins that could be interacting with the parasites during transmission for further characterization.

INSTRUMENT(S):

ORGANISM(S): Anopheles Stephensi (asian Malaria Mosquito) Plasmodium Falciparum (isolate 3d7) Plasmodium Berghei Anka Anopheles Gambiae (african Malaria Mosquito)

TISSUE(S): Saliva

DISEASE(S): Malaria

SUBMITTER: Tyler Schleicher  

LAB HEAD: Erol Fikrig

PROVIDER: PXD010121 | Pride | 2018-10-18

REPOSITORIES: Pride