Project description:To profile the expression of circulating microRNAs (miRNAs) of mice in exposure to intraperitoneal lipoteichoic acid (LTA) injection and compare that with those with lipopolysaccharide (LPS) injection
Project description:We collected whole genome testis expression data from hybrid zone mice. We integrated GWAS mapping of testis expression traits and low testis weight to gain insight into the genetic basis of hybrid male sterility.
Project description:To profile the expression of circulating microRNAs (miRNAs) of mice in exposure to intraperitoneal lipoteichoic acid (LTA) injection and compare that with those with lipopolysaccharide (LPS) injection C57BL/6 mice received intraperitoneal injections of 100 M-NM-<g of LTA originated from Bacillus subtilis, Streptococcus faecalis, and Staphylococcus aureus were killed 6 h and the whole blood samples were obtained for miRNA expression analysis using a miRNA array
Project description:To investigate the differences in microRNA expression profiles between fibrotic and normal livers, we performed microRNA microarrays for total RNA extracts isolated from mouse livers treated with carbontetrachloride (CCl4) or corn-oil for 10 weeks (n=3/group). MicroRNAs were considered to have significant differences in expression level when the expression difference showed more than two-fold change between the experimental and control groups at p<0.05. We found that 12 miRNAs were differentially expressed in CCl4-induced fibrotic liver.
