Project description:As a key factor for differentiation and development, IGF-1 has attracted scientists’ attention gradually in recent years. However, its exact effects in human umbilical cord-derived mesenchymal stem cells (UC-MSCs) are still unclear. In this study, we mainly investigated whether IGF-1 could affect some biological functions of UC-MSCs.
Project description:Quantitative shotgun proteomic analysis (TMT) of the effect of inhibition of MIR21 in the EV protein cargo of human, Umbilical cord-derived Mesenchymal Stem Cells.
Project description:This proteomic study aimed to investigate the in vitro transdifferentiation potential of equine umbilical cord-derived mesenchymal stem cells (EqUC-MSCs) using a protocol based on conditioned medium derived from equine facial nerve explant culture. This study contributes to the development of novel cell-based strategies for peripheral nerve repair in equine medicine.
Project description:screening of signature deterimes the individual variations in the therapeutic efficacy of human umbilical cord blood-derived mesenchymal stem cells There is paucity of information whether human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs) from separate donors might have different effects on improving myocardial repair after myocardial infarction (MI).
Project description:screening of signature deterimes the individual variations in the therapeutic efficacy of human umbilical cord blood-derived mesenchymal stem cells There is paucity of information whether human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs) from separate donors might have different effects on improving myocardial repair after myocardial infarction (MI). We screened cell surface genes by the comparing the cells that showed the best and worst efficacy, respectively, in repairing the infarcted myocardium of rats.
Project description:<p>To explore the effect of human umbilical cord mesenchymal stem cells (HUMSCs) on repairing CCl4-induced chronic liver injury in rats by intravenous injection and analyze the promising metabolites.</p>
