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Tick-borne encephalitis virus is an enveloped, pathogenic, RNA virus in the family Flaviviridae, genus Flavivirus. Viral particles are formed when the nucleocapsid, consisting of an RNA genome and multiple copies of the capsid protein, buds through the endoplasmic reticulum membrane and acquires ...

2023-01-06 | MTBLS6076 | MetaboLights
Early events of HIV-1 lifecycle, such as post-entry virus trafficking, uncoating and nuclear import, remain poorly understood due to limited information about virus-host interactions. We used a multidisciplinary approach. First, a mass spectrometry (MS)-based proteomics methodology enabled us to ide...
ORGANISM(S): Homo sapiens (Human) 
2021-01-04 | PXD020970 | Pride
The hepatitis E virus (HEV), a non enveloped RNA virus, causes viral hepatitis. The viral open reading frame 2 (ORF2) protein represents the capsid protein of HEV which is known to cause endoplasmic reticulum stress in ORF2 expressing cells. The initiation of endoplasmic reticulum stress induced apo...
ORGANISM(S): Homo sapiens 
Here, we present our investigation of the viral proteins of the capsid of adeno-associated viruses via top-down mass spectrometry on the LC timescale. Characterization was improved through the use of proton transfer charge reduction
ORGANISM(S): Human Aav 
2024-06-14 | MSV000095045 | MassIVE
Analysis of VEEV Capsid Interaction Sites
Due to the limited size of viral genomes, most viral proteins are multifunctional; yet most direct-acting antivirals are designed as single-function inhibitors. The dengue virus (DENV) capsid protein serves as a building block for new virions while also interacting with multiple host factors to remo...
ORGANISM(S): Homo sapiens (Human) 
2026-03-30 | PXD063557 | Pride
YFV Capsid changes to mRNA transcriptome of Huh7 cells
Chromatin accessibility analysis of Huh7 cells upon YFV capsid expression
Gene therapy has been adapted, from the laboratory to the clinic, to treat retinopathies. In contrast to subretinal route, intravitreal delivery of AAV vectors displays the advantage of bypassing surgical injuries, but the viral particles are more prone to be nullified by the host neutralizing facto...
ORGANISM(S): Adeno-associated Virus Predict_aav-6 
2023-12-04 | PXD047487 |
Sequencing of Echinococcus multilocularis densovirus non capsid protein 1 gene
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