Sort   by:  
 Page size 
ProteomicsSUMO-2 Orchestrates Chromatin Modifiers in Response to DNA Damage
Small Ubiquitin-like Modifiers play critical roles in the DNA Damage Response (DDR). To increase our understanding of SUMOylation in the mammalian DDR, we employed a quantitative proteomics approach to identify dynamically regulated SUMO-2 conjugates and modification sites upon treatment with the DN...
ORGANISM(S): Homo sapiens (Human) 
2015-03-16 | PXD001810 | Pride
Dna Damage Mms Sumo-2 Sumo Chromatin Repair Site 
TranscriptomicsArgonaute proteins couple chromatin silencing to alternative splicing (RNA IP-Seq)
While Argonaute (AGO) proteins play a major role in transcriptional gene silencing (TGS) in many organisms, their role in the nucleus of somatic mammalian cells remains elusive. Here, we have purified AGO1 and AGO2 chromatin-embedded complexes, and found these proteins associated with previously des...
ORGANISM(S): Homo sapiens 
2012-09-10 | E-GEOD-39748 | biostudies-arrayexpress
TranscriptomicsGenetic control of yeast chromatin acetylation epi-polymorphisms
Genetic control of yeast chromatin acetylation epi-polymorphisms
ORGANISM(S): Saccharomyces cerevisiae 
2012-09-21 | E-MTAB-575 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Saccharomyces cerevisiae knock-outs of non-essential chromatin modifiers
Non-essential knockouts of chromatin modifiers have been investigated by expression profiling.
ORGANISM(S): Saccharomyces cerevisiae 
2011-08-05 | E-TABM-1074 | biostudies-arrayexpress
TranscriptomicsGene deletion expression profiles of yeast chromatin modifiers
Packaging of DNA into chromatin has a profound impact on gene expression. To understand how changes in chromatin influence transcription, we analyzed 165 mutants of chromatin machinery components in Saccharomyces cerevisiae. mRNA expression patterns change in 80% of mutants, always with specific eff...
ORGANISM(S): Saccharomyces cerevisiae 
2011-05-23 | E-GEOD-25909 | biostudies-arrayexpress
TranscriptomicsArgonaute proteins couple chromatin silencing to alternative splicing (exon array)
While Argonaute (AGO) proteins play a major role in transcriptional gene silencing (TGS) in many organisms, their role in the nucleus of somatic mammalian cells remains elusive. Here, we have purified AGO1 and AGO2 chromatin-embedded complexes, and found these proteins associated with previously des...
ORGANISM(S): Mus musculus 
2012-09-10 | E-GEOD-39746 | biostudies-arrayexpress
UnknownCoordinated regulation of chromatin modifiers reflects organised epigenetic programming in mouse oocytes.
Not available
S-EPMC11971813 | biostudies-literature
UnknownInference of interactions between chromatin modifiers and histone modifications: from ChIP-Seq data to chromatin-signaling.
Not available
S-EPMC4267652 | biostudies-literature
TranscriptomicsArgonaute proteins couple chromatin silencing to alternative splicing
This SuperSeries is composed of the following subset Series: GSE39746: Argonaute proteins couple chromatin silencing to alternative splicing (exon array) GSE39748: Argonaute proteins couple chromatin silencing to alternative splicing (RNA IP-Seq) Refer to individual Series
ORGANISM(S): Mus musculus 
2012-08-22 | E-GEOD-39749 | biostudies-arrayexpress
ProteomicsSUMOylation regulates chromatin protein network and accessibility at glucocorticoid receptor-binding sites
Glucocorticoid receptor (GR) is an essential transcription factor (TF), controlling metabolism, development and immune responses. SUMOylation regulates chromatin occupancy and target gene expression of GR in a locus-selective manner, but the mechanism of regulation has remained elusive. Here, we sho...
ORGANISM(S): Homo sapiens (Human) 
2021-09-08 | PXD015183 | Pride
Glucocorticoid receptor Proteomics Chromatin regulation Sumoylation Transcription factors 
Sort   by:  
 Page size