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ProteomicsGlycoproteoforms of Integrins α2 and β1 in Megakaryocytes in the Occurrence of Primary Myelofibrosis
Primary myelofibrosis (PMF) is a myeloproliferative neoplasm prone to leukemic transformation, for which limited treatment is available. Amongst individuals diagnosed with PMF, the most prevalent mutation is the JAK2V617F somatic point mutation that activates the Janus kinase 2 (JAK2) enzyme. Our ea...
ORGANISM(S): Mesocricetus auratus (Golden hamster) Mus musculus (Mouse) 
2022-02-22 | PXD030550 | Pride
Integrins  megakaryocytes  primary myelofibrosis  lc-ms/ms  glycopeptiforms 
UnknownCognitive decline in older adults with type 2 diabetes: Unraveling site-specific glycoproteomic alterations.
Not available
S-EPMC12061096 | biostudies-literature
ProteomicsGlycoproteome-Wide Discovery of Cortical Glycoproteins That May Provide Cognitive Resilience in Older Adults
Background and Objectives Molecular omics studies have identified proteins related to cognitive resilience but unrelated to Alzheimer disease and Alzheimer disease–related dementia (AD/ADRD) pathologies. Posttranslational modifications of proteins with glycans can modify protein function. In this s...
ORGANISM(S): Homo sapiens (Human) 
2025-12-24 | PXD072371 | Pride
Brain Ad Glycoproteomics Human Cognition 
UnknownCharacterization of Glycoproteoforms of Integrins α2 and β1 in Megakaryocytes in the Occurrence of JAK2V617F Mutation-Induced Primary Myelofibrosis.
Not available
S-EPMC8968581 | biostudies-literature
ProteomicsCognitive Decline in Older Adults with Type 2 Diabetes: Unraveling Site-Specific Glycoproteomic Alterations
Type 2 diabetes (T2D) is consistently associated with an elevated risk of cognitive decline and dementia. The underlying molecular mechanisms relating T2D to cognitive decline remain unclear, impeding the ability to detect the earliest stages of cognitive decline in older adults with T2D, consequent...
ORGANISM(S): Homo sapiens (Human) 
2025-02-16 | PXD050780 | Pride
Glycosylation Glycation Serum Glycoproteomics Plasma Cognition 
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