Sort   by:  
 Page size 
TranscriptomicsAnalysis of human myeloma cell lines expressing beta 3 integrin
The aim of these experiments was designed to compare gene expression in human myeloma cell lines expressing beta 3 integrin vs counterpart cell lines that do not express beta 3 integrin. Keywords: Gene expression,cell lines, siRNA Phenotype characterization of both primary and cultured myeloma plas...
ORGANISM(S): Homo sapiens 
2010-05-19 | E-GEOD-15867 | biostudies-arrayexpress
TranscriptomicsCre-mediated deletion of b1 integrin in pancreatic b-cells
In this study, we investigated the function of beta integrins in developing islet beta-cells by targeting the deletion of exon 3 of the B1 integrin gene using a Cre-lox approach. Our results demonstrate that this class of integrin receptors is critically important for proper beta cell expansion duri...
ORGANISM(S): Mus musculus 
2013-07-31 | E-MEXP-3736 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse C2C12 myoblast induced with tetracycline to enhance integrin alpha7 expression
Analysis of C2C12 myoblast induced with tetracycline to enhance integrin alpha7 expression. Integrin alpha7 is the major laminin binding integrin in muscle cells. Enhancing its expression has been demonstrated to alleviate pathology in a murine model of Duchenne muscular dystrophy. Results of this s...
ORGANISM(S): Mus musculus 
2008-06-16 | E-GEOD-8312 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse skeletal muscle of integrin alpha7 overexpressing animals vs controlls
Analysis of integrin alpha7 transgenic mice skeletal muscle transcription profiles comparing to wild type controls. Integrin alpha7 is the major laminin binding integrin in muscle cells. Enhancing its expression has been demonstrated to alleviate pathology in a murine model of Duchenne muscular dyst...
ORGANISM(S): Mus musculus 
2008-06-16 | E-GEOD-8313 | biostudies-arrayexpress
GenomicsGene expression from ErbB2-driven mamamry tumors (MMTV-NIC model) with beta 1 integrin KO, beta 3 integrin KO or beta 1/beta 3 double KO
Gene expression from ErbB2-driven mamamry tumors (MMTV-NIC model) with beta 1 integrin KO, beta 3 integrin KO or beta 1/beta 3 double KO
PRJNA561609 | ENA
TranscriptomicsGene expression in b1-integrin wild-type and knockout mouse heart
Growth and expansion of ventricular chambers is essential during cardiogenesis and is achieved by proliferation of cardiac progenitors that are not fully differentiated. Disruption of this process can lead to prenatal lethality. In contrast, adult cardiomyocytes achieve growth through hypertrophy ra...
ORGANISM(S): Mus musculus 
2009-01-14 | E-GEOD-14411 | biostudies-arrayexpress
ProteomicsMesenchymal stem cell integrin-associated complexes
The composition and stiffness of the extracellular matrix (ECM) environment that surrounds Multipotent mesenchymal stem cells (MSCs) stem cells dictates transcriptional programming, thereby affecting stem cell lineage decision-making. Cells sense force between themselves and their microenvironment ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-20 | MSV000079956 | MassIVE
TranscriptomicsDepletion of beta1 integrins in triple negative breast cancer cells causes extensive alterations in gene expression profiles
Interactions with the extracellular matrix (ECM) through integrin adhesion receptors provide cancer cells with physical and chemical cues that act in concert with growth factors to support survival and proliferation. Preclinical studies testing beta1 integrin antagonists in (breast) cancer models h...
ORGANISM(S): Mus musculus 
2014-02-11 | E-MTAB-2185 | biostudies-arrayexpress
ProteomicsIntegrin beta 3 regulates cellular senescence by activating the TGFβ pathway
Cellular senescence is an important in vivo mechanism that prevents the propagation of damaged cells. However, the precise mechanism(s) regulating senescence are not well characterized. Here, we find that ITGB3 (integrin beta 3 or β3) is epigenetically regulated by the Polycomb protein CBX7. β3 expr...
ORGANISM(S): Homo sapiens (Human) 
2017-03-09 | PXD005717 | Pride
Senescence Silac Cbx7 
TranscriptomicsAnalysis of human myeloma cell lines expressing beta 3 integrin
The aim of these experiments was designed to compare gene expression in human myeloma cell lines expressing beta 3 integrin vs counterpart cell lines that do not express beta 3 integrin. Keywords: Gene expression,cell lines, siRNA
ORGANISM(S): Homo sapiens 
2009-04-29 | GSE15867 | GEO
Sort   by:  
 Page size