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ProteomicsMannose-6-phosphate isomerase functional status shapes a rearrangement in the proteome and degradome of mannose-treated melanoma cells
Metabolic reprogramming is a ubiquitous feature of transformed cells, comprising one of the hallmarks of cancer and enabling neoplastic cells to adapt to new environments. Accumulated evidence reports on the failure of some neoplastic cells to convert mannose-6-phosphate into fructose-6-phosphate, t...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-02-16 | MSV000094098 | MassIVE
ProteomicsMouse kidney Mannose-6-Phosphate Glycoproteome LC-MSMS
This is the raw data and Byonic search results of mouse kidney Mannose-6-Phosphate glycoproteome.
ORGANISM(S): Mus musculus (Mouse) 
2020-03-11 | PXD012402 | Pride
Mouse kidney  mannose-6-phosphate  glycoproteome 
ProteomicsMouse Liver Mannose-6-Phosphate Glycoproteome LC-MSMS
This is the raw data and Byonic search results of mouse liver Mannose-6-Phosphate glycoproteome.
ORGANISM(S): Mus musculus (Mouse) 
2020-03-11 | PXD012404 | Pride
Mouse liver  mannose-6-phosphate  glycoproteome 
ProteomicsMouse Heart Mannose-6-Phosphate Glycoproteome LC-MSMS
This is the raw data and Byonic search results of mouse mouse brain Mannose-6-Phosphate glycoproteome.
ORGANISM(S): Mus musculus (Mouse) 
2020-03-11 | PXD012401 | Pride
Mouse heart  mannose-6-phosphate  glycoproteome 
ProteomicsMouse Lung Mannose-6-Phosphate Glycoproteome LC-MSMS
This is the raw data and Byonic search results of mouse mouse lung Mannose-6-Phosphate glycoproteome.
ORGANISM(S): Mus musculus (Mouse) 
2020-03-11 | PXD012403 | Pride
Mouse lung  mannose-6-phosphate  glycoproteome 
ProteomicsMouse Brain Mannose-6-Phosphate Glycoproteome LC-MSMS
This is the raw data and Byonic search results of mouse mouse brain Mannose-6-Phosphate glycoproteome.
ORGANISM(S): Mus musculus (Mouse) 
2020-03-11 | PXD012400 | Pride
Mouse brain  mannose-6-phosphate  glycoproteome 
ProteomicsMouse lung N-glycoproteome, phosphoproteome, and M6P glycoproteome
This is the raw data and Byonic search results of mouse mouse lung N-glycoproteome, phosphoproteome, and Mannose-6-Phosphate glycoproteome.
ORGANISM(S): Mus musculus (Mouse) 
2022-01-11 | PXD020196 | Pride
Mannose-6-phosphate glycosylation Phosphoproteome Mouse Lung Glycoproteome 
ProteomicsAnalysis of intact mannose-6-phosphate glycopeptides
We have repurposed standard phosphoproteomics workflow based on Fe3+IMAC for enrichment ofmannose-6-phosphate modified glycopeptides. This worklfow was used to profile lysosomal acid hydrolases in HeLa and CHO cell lines. We have combined this approach with CRISPR/Cas9 KO of acid phosphatases 2 and ...
ORGANISM(S): Homo sapiens (Human) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) 
2018-12-18 | PXD010333 | Pride
Imac Hela M6p Glycopeptide Cho 
ProteomicsLC-MS/MS analysis of Mannose 6-phosphate containing proteins
Mucolipidosis III gamma (MLIII) is clinically characterized by onset of first symptoms at an average of 5 years such as stiffness of hands and shoulders, claw hand deformities, scoliosis and progressive destruction of hip joints. The disease is caused by mutations in GNPTG encoding the gamma-subunit...
ORGANISM(S): Mus musculus (Mouse) 
2018-06-06 | PXD007546 | Pride
Secreted proteins : mouse embryonic fibroblasts Mannose 6-phosphate affinity purification 
ProteomicsComparative analyses of the N-glycoproteomes in HCT116 cancer cells and their non-tumorigenic DNMT1/3b double knockout (DKO1) cells and insight into the Mannose-6-phosphate pathway
N-glycoproteomic analyses provide valuable resources for investigation of cancer mechanisms, biomarkers, and therapeutic targets. Here, we mapped and compared the site-specific N-glycoproteomes of colon cancer HCT116 cells and isogenic non-tumorigenic DNMT1/3b double knockout (DKO1) cells using Fbs...
ORGANISM(S): Homo sapiens (Human) 
2023-01-17 | PXD035301 | Pride
Mannose-6-phosphate (m6p) Fbs1-gyr N-glycoproteome N-glycosylation Paucimannose 
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