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GenomicsFunctional heterogeneity of meniscal fibrochondrocytes and microtissue models is dependent on modality of fibrochondrocyte isolation
Functional heterogeneity of meniscal fibrochondrocytes and microtissue models is dependent on modality of fibrochondrocyte isolation
PRJNA1080547 | ENA
ProteomicsTelmisartan is neuroprotective in a hiPSC-derived spinal microtissue model for C9orf72-ALS via inhibition of neuroinflammation
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease characterized by motor neurons (MN) loss. Mutations in C9orf72 are the leading genetic cause of ALS and involve hexanucleotide repeat expansions (HRE) in the noncoding region of the gene. Neuroinflammation is a key featur...
ORGANISM(S): Homo sapiens (Human) 
2025-07-28 | PXD057067 | Pride
Neuroinflammation  neurodegeneration  amyotrophic lateral sclerosis  c9orf72  human pluripotent stem cells  cellular interactions  motor neurons  astrocytes  microglia  spinal cord  triculture  three-dimension  microtissue  drug screen  sartans  telmisartan 
UnknownMicrotissue-Based Bioink as a Chondrocyte Microshelter for DLP Bioprinting.
Not available
S-EPMC11468467 | biostudies-literature
TranscriptomicsFunctional heterogeneity of meniscal fibrochondrocytes and microtissue models is dependent on modality of fibrochondrocyte isolation
Collagenase digestion (d) and cellular outgrowth (og) are the current modalities of meniscus fibrochondrocytes (MFC) isolation for bioengineering and mechanobiology related studies. However, how these modalities may impact study outcomes are unknown. Here, we show og- and d-isolated MFC have distinc...
ORGANISM(S): Homo sapiens 
2024-09-30 | GSE259265 | GEO
UnknownInjectable BMSC-Based Extracellular Matrix-Mimicking Microtissue for Myocardial Infarction Repair.
Not available
S-EPMC12806379 | biostudies-literature
UnknownHelical nanofiber yarn enabling highly stretchable engineered microtissue.
Not available
S-EPMC6511022 | biostudies-literature
UnknownLung Microtissue Array to Screen the Fibrogenic Potential of Carbon Nanotubes.
Not available
S-EPMC4980669 | biostudies-literature
UnknownProduction of Multiple Cell-Laden Microtissue Spheroids with a Biomimetic Hepatic-Lobule-Like Structure.
Not available
S-EPMC11469225 | biostudies-literature
UnknownParallelized Wireless Sensing System for Continuous Monitoring of Microtissue Spheroids.
Not available
S-EPMC7115843 | biostudies-literature
UnknownFunctional tissue-engineered microtissue formed by self-aggregation of cells for peripheral nerve regeneration.
Not available
S-EPMC8744299 | biostudies-literature
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