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ProteomicsZIKV-infected human NPCs LC-MS
In this study, proteomic analysis on ZIKV-infected primary human fetal neural progenitor cells (NPCs) revealed that virus infection altered levels of cellular proteins involved in NPC proliferation, differentiation and migration.
ORGANISM(S): Homo sapiens (Human) 
2018-06-25 | PXD009343 | Pride
Human npcs Zikv infection 
GenomicsDNA methylation profiles in 3 mutant NPCs and wt NPCs (control, empty vector) at 10 days
DNA methylation profiles in 3 mutant NPCs and wt NPCs (control, empty vector) at 10 days
PRJNA1117425 | ENA
GenomicsDNA methylation profiles in seven mutant NPCs and wt NPCs (control, empty vector) at 2 days
DNA methylation profiles in seven mutant NPCs and wt NPCs (control, empty vector) at 2 days
PRJNA1117414 | ENA
TranscriptomicsComparing Control and Schizophrenic hiPSC-derived NPCs
Cell-based models of many neurological and psychiatric diseases, established by reprogramming patient somatic cells into human induced pluripotent stem cells (hiPSCs), have now been reported. While numerous reports have demonstrated that neuronal cells differentiated from hiPSCs are electrophysiolo...
ORGANISM(S): Homo sapiens 
2014-04-01 | E-GEOD-40102 | biostudies-arrayexpress
GenomicsDNA methylation profiles in seven mutant NPCs and wt NPCs (control, empty vector) at 2 days [LM17-Lm24]
DNA methylation profiles in seven mutant NPCs and wt NPCs (control, empty vector) at 2 days [LM17-Lm24]
PRJNA1117422 | ENA
ProteomicsCo-IP protein identification of WT/MT IVNS1ABP in isogenic iPSCs derived NPCs
We identified a new disease characterized by severe neurological deficits in addition to progeria symptoms. It is caused by IVNSABP gene mutation. The association between IVNS1ABP and aging has never been reported before. By generating isogenic iPSCs from the patients’ fibroblasts and differentiatin...
ORGANISM(S): Homo sapiens (Human) 
2026-01-23 | PXD053645 | Pride
Ipscs Npcs Co-ip Ivns1abp 
ProteomicsProteomic analysis of WT and AP-2 KO NPCs at DIV3
Full proteome analysis of WT and AP-2 KO NPCs at DIV3 to detect dysregulated proteins.
ORGANISM(S): Mus musculus (Mouse) 
2023-12-11 | PXD047200 | Pride
Centrosome Ap-2 Microtubules Neuronal progenitors 
TranscriptomicsATAC-seq of iPSC-derived NPCs and neurons
To connect the neuronal developmental disorders associated GWAS signal to their target effector genes, we performed an integrated analysis of transcriptomics, epigenomics and chromatin conformation changes in an in vitro cellular model. Induced human pluripotent stem cell–derived neural progenitor c...
ORGANISM(S): Homo sapiens 
2021-05-27 | E-MTAB-9087 | biostudies-arrayexpress
GenomicsChIP-Seq of Sox2 and Brn2 in ESCs, NPCs, and differentiating ESCs
We analyzed the genome-wide binding of Sox2 and POU factor partner factors, Oct4 in ESCs (using published datasets PMID:18692474 and GSM307137, GSM307154, GSM307155) and Brn2 in NPCs. We found that Sox2 and Oct4 co-occupied a large subset of promoters and enhancers in ESCs, but that Sox2 and Brn2 co...
ORGANISM(S): Mus musculus 
2013-02-20 | E-GEOD-35496 | biostudies-arrayexpress
TranscriptomicsNext Generation Sequencing Compares Effects of microRNA-9 perturbation in control and SZ hiPSC NPCs
To follow-up findings that miR-9 was abundantly expressed in control NPCs, significantly down-regulated in a subset of SZ NPCs, and that miR-9 levels/activity, neural migration and diagnosis were strongly correlated, we tested the effect of manipulating miR-9 at cellular, proteomic and transcriptomi...
ORGANISM(S): Homo sapiens 
2016-04-13 | E-GEOD-80170 | biostudies-arrayexpress
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