uveitis - OmicsDI

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CHEBI ID

CHEBI:192306 (2)
CHEBI:34276 (2)
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CHEBI:169194 (2)
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CHEBI:27838 (2)
CHEBI:68567 (2)
CHEBI:59783 (2)
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CHEBI:30797 (2)
CHEBI:17596 (2)
CHEBI:139454 (1)
CHEBI:192344 (1)
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CHEBI:192339 (1)
CHEBI:192338 (1)
CHEBI:192336 (1)
CHEBI:192334 (1)
CHEBI:173584 (1)
CHEBI:192332 (1)

Metabolite Name

17-Hydroxy-9,11,13,15-octadecatetraynoic acid (2)
4,5-Dimethyloxazole (2)
Pyrimidine (2)
1-(1-Pyrrolidinyl)-2-propanone (2)
Trimethylaminoacetone (2)
Diferuloylputrescine (2)
D-1-Piperideine-2-carboxylic acid (2)
1-(9H-Pyrido[3,4-b]indol-1-yl)-1,4-butanediol (2)
N1-Methyl-4-pyridone-3-carboxamide (2)
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2-Hydroxy-3-methylbutyric acid (2)
N-Acetyl-L-aspartic acid (2)
4-Nitrophenol (2)
L-Lysine (2)
7-Methylguanine (2)
Zingerone (2)
Benzoic acid (2)
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Tauroursodeoxycholic acid (2)
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protozoa (1)
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1996 (1)

Lab affiliation

Department of Ophthalmology, University Medical Center Utrecht, University of Utrecht, Utrecht, Netherlands. Center for Translational Immunology, University Medical Center Utrecht, University of Utrecht, Utrecht, Netherlands. (1)
McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA (1)
Core Facility Metabolomics and Proteomics, Helmholtz Center Munich, German Research Center for Environmental Health, Munich, Germany (1)
Department of Veterinary Sciences, Ludwig-Maximilians-University of Munich, Munich, Germany Department of Experimental Ophthalmology, Philipps University of Marburg, Marburg, Germany (1)
The first affiliated hospital of Chongqing Medical University (1)
Eye & Vison Health, Flinders University School of Medicine Flinders Medical Center Flinders University Australia (1)
LMU Munich, Chair of Animal Physiology (1)
Ophthalmology Medical Center，The First Affiliated Hospital of Chongqing Medical University，Chongqing Key Laboratory for the Prevention and Treatment of Major Blinding Eye Diseases，Chongqing Branch (Municipality Division) of National Clinical Research Centre for Ocular Diseases (1)
Department of Ophthalmology, Hadassah Medical Center, Jerusalem, Israel (1)
Department of Ophthalmology, Byers Eye Institute, Stanford University, Palo Alto, CA (1)
School of Optometry, The Hong Kong Polytechnic University,Kowloon, Hong Kong SAR, China (1)
Section of Pediatrics, Pediatrics, Department of Clinical Sciences Lund, Skåne University Hospital, Lund University,Lund, Sweden Wallenberg Centre for Molecular Medicine, Lund University, Lund, Sweden (1)
Research Unit Protein Science, Helmholtz Center Munich, Research Center for Environmental Health (GmbH), Neuherberg,Germany (1)
Research Unit Protein Science, Helmholtz Center Munich, German Research Center for Environmental Health GmbH, Germany (1)
Helmholtz Zentrum München, Neuherberg, Germany (1)

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Comparison of intestinal microbes and metabolites in active VKH versus acute anterior uveitis associated with ankylosing spondylitis

BACKGROUND: It has been reported that the gut microbiome is involved in the pathogenesis of uveitis, but the specific pathogenic microbes and metabolites in different types of uveitis are still unclear.

METHODS:&...

2023-12-12 | MTBLS7936 | MetaboLights

High-dose capsaicin exacerbates uveitis by disrupting intestinal ho-meostasis and upregulating IL-17

Purpose: To determine whether capsaicin (CAP) exacerbates experimental autoimmune uveitis (EAU) and whether this effect is associated with impaired intestinal homeostasis, gut microbiota re-modeling, and altered metabolic profiles. Methods: An EAU mouse model was used to evaluate the dose-dependent ...

2026-07-23 | MTBLS15144 | MetaboLights

Tear proteome of patients with non-infectious uveitis responders and non-responders to adalimumab

Proteomic anaysis of tear samples from patients with non-infectious uveitis responders and non-responders to adalimumab included in a cross-sectional study

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

MSV000095892 | MassIVE

Retinal proteomic analysis in a mouse model of endotoxin-induced uveitis using a data-independent acquisition-based mass spectrometry

Endotoxin-induced uveitis (EIU) in rodents is a good animal model to study uveitis and associated acute retinal inflammation. To understand the pathogenic mechanism of uveitis and screen the potential targets for treatment, we analyzed the retinal proteomic profiles of EIU and normal C57BL/6J mice u...

ORGANISM(S): Mus musculus (Mouse)

2022-08-12 | PXD033532 | Pride

equine CD4+ T cells show changed membrane protein expression in autoimmune uveitis

Through this comparative proteomic study of equine CD4+ cells 376 membrane proteins could be identified. Several proteins showed changed abundance in horses affected by a spontaneous autoimmune disease (equine recurrent uveitis, ERU). Findings provide novel knowledge about changes in the CD4+ immune...

ORGANISM(S): Equus caballus (Horse)

2017-01-09 | PXD005384 | Pride

Lc-msms mass spectrometry analysis Membrane proteins Cd4+ t cells Autoimmune uveitis Equine recurrent uveitis

Proteome changes in retinal Mueller glial cells from a spontaneous equine model for autoimmune uveitis compared to healthy controls

Retinal Müller glial cells (RMG) play a central role in retinal neuroinflammation, actively participating in the immune response and adopting a dynamic inflammatory phenotype. However, the precise functions of RMG in retinal inflammation remain incompletely understood. In this study, we investigated...

ORGANISM(S): Equus caballus (Horse)

2025-05-07 | PXD058170 | Pride

Quantitative label-free lc-ms/ms retinal neuroinflammation autoimmune uveitis equine recurrent uveitis (eru) spontaneous equine animal model retinal mueller glial cells (rmg)

Proteome dynamcis in biobanked horse peripheral blood derived lymphocytes (PBL) with induced autoimmune uveitis

Equine recurrent uveitis (ERU) is the only spontaneous model for recurrent autoimmune uveitis in humans, where T cells target retinal proteins. Differences between normal and autoaggressive lymphocytes were identified in this study by analyzing peripheral blood derived lymphocytes (PBL) proteomes fr...

ORGANISM(S): Equus caballus (Horse)

2017-08-31 | PXD005580 | Pride

Frozen Lc-msms Cfa Lymphocytes Inflammation Autoimmune

Proteomic Analysis of Intermediate Uveitis

Liquid vitreous biopsies were collected from two groups: eyes from control subjects (n=4) undergoing pars plana vitrectomy to remove an idiopathic macular hole (IMH), and eyes from test subjects (n=4) with IU. Vitreous samples were analyzed using a liquid chromatography-tandem mass spectrometry (LC-...

ORGANISM(S): Homo sapiens (Human)

2022-02-22 | PXD011972 | Pride

Vitreous Proteomics Intermediate uveitis Biomarker Lc-ms/ms

High salt diet and uveitis

PRJEB65938 | ENA

Uveitis output in high-impact clinical ophthalmology journals: a bibliometric analysis.

Not available

S-EPMC11937460 | biostudies-literature

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