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MetabolomicsSpatial multi-omics inference of diabetes mellitus triggering pancreatic cancer growth through cholesterol-induced neutrophil extracellular traps

Spatial multi-omics inference of diabetes mellitus triggering pancreatic cancer growth through cholesterol-induced neutrophil extracellular traps

2025-11-26 | MTBLS12782 | MetaboLights
OtherProteomics of Fuchs- Endothelial Corneal Dystrophy support that the extracellular matrix of Descemet-s membrane is disordered.
Data from ProteomeXchange, PXD ID: PXD000746. Experiment: label-free, file: 2012-10-05 - ETP - Fuchs - Control - 3-2.mgf. Published as part of J Proteome Res. 2014 May 21 . From the Abstract: {{i}} Fuchs- endothelial corneal dystrophy (FECD) is a major corneal disorder affecting the innermost part ...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM32310000394 | GPMDB
Resource Reanalysis 
TranscriptomicsTranscription profiling of human rheumatoid arthritis patients derived synovial fibroblasts - using boolean network models for extracellular matrix formation
Background ; Rheumatoid arthritis (RA) is a chronic inflammatory disease, characterized by joint destruction and perpetuated by the synovial membrane (SM). In the inflamed SM, activated synovial fibroblasts (SFB) form the major cell type promoting development and progression of the disease by an abn...
ORGANISM(S): Homo sapiens 
2009-08-07 | E-GEOD-13837 | biostudies-arrayexpress
ProteomicsMouse kidney glomerular extracellular matrix LC-MSMS
Across the spectrum of human disease there are significant changes in the composition and organisation of extracellular matrix (ECM). Furthermore, disease severity can vary according to race and sex, yet mechanisms for these variations are unclear. Using the kidney glomerulus as a model system, we t...
ORGANISM(S): Mus musculus (Mouse) 
2016-07-09 | PXD000811 | Pride
Lc-msms Mouse Kidney Glomerular Extracellular matrix 
ProteomicsThe extracellular matrix landscape identifies different etiologies behind bicuspid and tricuspid aortic valve degeneration
The molecular basis of aortic valve degeneration (AVD) is unclear. The extracellular matrix (ECM) of the valve is in dynamic reciprocity with its surrounding microenvironment and contains molecular traits of the pathophysiological processes. We compared abundances of ECM proteins from excised valve ...
ORGANISM(S): Homo sapiens (Human) 
2023-09-03 | PXD025002 | Pride
Ecm Lc-ms/ms Human Aortic valve degeneration Extracellular matrix 
ProteomicsExtracellular Matrix Proteomics of Human Heart Failure
MS analysis of human cardiac samples from left ventricles of patients undergoing cardiac transplantation due to ischaemic heart failure. Analysis of intracellular protein enriched extracts.
ORGANISM(S): Homo sapiens (Human) 
2021-12-15 | PXD028906 | Pride
Extracellular matrix Human Heart failure 
ProteomicsITGA3 neg. human keratinocytes
Integrin alpha3beta1, a major epidermal adhesion receptor is critical for organization of the basement membrane during development and wound healing. Integrin alpha3 deficiency leads to interstitial lung disease, nephrotic syndrome and epidermolysis bullosa (ILNEB), an autosomal recessive multiorgan...
ORGANISM(S): Homo sapiens (Human) 
2018-11-27 | PXD009896 | Pride
Keratinocyte Skin Human Lc-ms/ms 
UnknownAltered protein levels in the isolated extracellular matrix of failing human hearts with dilated cardiomyopathy.
Not available
S-EPMC5494967 | biostudies-literature
ProteomicsCD81 facilitates tumor cell clustering and metastasis in triple negative breast cancer
Tumor-initiating cells with reprogramming plasticity and/or de-differentiation attributes have been thought to initiate primary tumor development as well as to regenerate secondary tumors in metastatic organs; however, the molecular mechanisms are not fully understood. We previously found that breas...
ORGANISM(S): Homo Sapiens (human) 
2022-10-18 | PXD029529 | JPOST Repository
UnknownAssembly of fibronectin extracellular matrix.
Not available
S-EPMC3628685 | biostudies-literature
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