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TranscriptomicsExpression data from 5azaC- or gallic acid-treated human lung cancer H1299 cell line
Gallic acid (also known as 3,4,5-trihydroxybenzoic acid, GA), a naturally occurring phenolic acid, is a major constituent of tea and red wine. It has been demonstrated that GA possess anti-cancer activities. We found the epigenetic effect of GA in tobacco-associated human cancer cell lines. In this ...
ORGANISM(S): Homo sapiens 
2018-02-14 | GSE99993 | GEO
TranscriptomicsDemethylation profiling of human lung cancer cell lines
The goal of this study is to identify those genes that are commonly silenced by DNA-methylation in lung cancer cell lines. Experiment Overall Design: Ten lung cancer cell lines (Calu 1, Hotz, U1752, Calu 6, ZL25, Calu3, SW2, A549, H125, and H 460) were analyzed before and after the treatment with 5-...
ORGANISM(S): Homo sapiens 
2009-08-09 | E-GEOD-14315 | biostudies-arrayexpress
ProteomicsRNF25 provides tolerance towards chemotherapeutic mRNA damage
Many chemotherapeutic agents damage DNA, which is believed to mediate their therapeutic efficacy. However, most of these agents act pleiotropically and also damage RNA, raising questions about the contribution of RNA damage to therapeutic outcomes and whether cells possess factors that protect them ...
ORGANISM(S): Homo sapiens (Human) 
2026-03-14 | PXD059287 | Pride
Rna damage Gcn2 5azac Gcn1 Rnf25 
GenomicsHomo sapiens
Expression data from 5azaC- or gallic acid-treated human lung cancer H1299 cell line
PRJNA390295 | ENA
GenomicsSmcHD1 genome-wide occupancy
To identify SmcHD1 genome-wide occupancy relative to global level of DNA methylation, we generated anti-SmcHD1 antiserum and used it in chromatin immunoprecipitation assay. We used SH-SY5Y neurobalstoma cells treated with DNA demethylating agent 5azaC for 72 hours to induce global loss of DNA methyl...
ORGANISM(S): Homo sapiens 
2019-05-22 | GSE99227 | GEO
UnknownING1 and 5-azacytidine act synergistically to block breast cancer cell growth.
Not available
S-EPMC3423394 | biostudies-literature
UnknownDynamic changes in methylome and transcriptome patterns in response to methyltransferase inhibitor 5-azacytidine treatment in citrus.
Not available
S-EPMC5737679 | biostudies-literature
Methylation profilingThe comparative methylome analysis of tumor microenvironment from African American and Non- White Hispanic American prostate cancer
We investigated differences in DNA methylation in tumor-adjacent stroma (TAS) of African Americans (AA) (n=17) and European Americans (EA) (n=15) to uncover differences that might contribute to a higher rate of aggressive prostate cancer (PCa) in AA men. We performed methyl binding domain sequencing...
ORGANISM(S): Homo sapiens 
2025-07-30 | GSE261520 | GEO
GenomicsEntamoeba histolytica
Expression data of E. histolytica trophozoites treated with 5AzaC
PRJNA98825 | ENA
UnknownAn MHV-68 Mutator Phenotype Mutant Virus, Confirmed by CRISPR/Cas9-Mediated Gene Editing of the Viral DNA Polymerase Gene, Shows Reduced Viral Fitness.
Not available
S-EPMC8227558 | biostudies-literature
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