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This study investigates how differentiated white adipocytes adapt to cooler temperatures by remodeling their acetyl-lysine–modified proteome. Differentiated adipocytes were cultured at 37°C or 31°C for 12 days to induce temperature-dependent physiological and biochemical changes. To profile acetylat...
ORGANISM(S): Mus musculus (Mouse) 
2026-09-07 | PXD079423 | Pride
Total H4 and acetyl H4 IP, time course Total H4 and acetyl H4 occupancy, Snf2 occupancy, gene expression analysis Keywords: stress response, time course
ORGANISM(S): Saccharomyces cerevisiae 
2008-03-17 | GSE7665 | GEO
Total H4 and acetyl H4 IP, time course Total H4 and acetyl H4 occupancy, Snf2 occupancy, gene expression analysis Keywords: stress response, time course S cerevisiae were subjected to heat shock and stationary phase stress. The histone occupancy and H4 acetylation levels were monitored in parallel w...
ORGANISM(S): Saccharomyces cerevisiae 
Emerging evidence points to protein acetylation as a nexus at the interface of virus-host interactions. However, global protein acetylation is understudied during infection, and the temporal control and function of acetylation in the context of infection remains poorly understood. Here, we present t...
ORGANISM(S): Homo sapiens (Human) 
2018-11-21 | PXD009839 | Pride
We conducted a combining isobaric tag-based TMT labeling followed by enrichment of lysine acetylated peptides by Acetyl-Lysine Immunoprecipitation (IP) method as Acetylomics study on MDA-MB-231 treated with safranal.
ORGANISM(S): Homo sapiens (Human) 
2022-08-30 | PXD036333 | Pride
PRMT1 plays pivotal roles in normal and disease biology. Understanding its regulation is crucial for therapeutic targeting. We demonstrate that p300-mediated acetylation of PRMT1 at K228 triggers degradation via FBXL17-dependent ubiquitination at K145. Using mass spectrometry, cellular biochemistry,...
ORGANISM(S): Homo sapiens 
2026-07-31 | GSE304181 | GEO
We propose the isotopically labeled Ac-IP (acetyl-isoleucine-proline) tag for multiplexed quantification of peptides at the MS1 level in the data-independent acquisition (DIA) mode. Differentially labeled peptides have distinct precursor ions carrying the quantitative information but identical MS2 s...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2021-06-07 | PXD022606 | Pride
Stress-dependent dynamics of chromatin remodeling in yeast: Dual roles for SWI/SNF in heat shock stress response
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