Sort   by:  
 Page size 
ProteomicsSynovial fluid proteome changes in ACL injury-induced posttraumatic osteoarthritis: proteomics analysis of porcine knee synovial fluid
In the current work, we used an isotopically labeled high resolution LC MS/MS-based proteomics approach to analyze the protein profile of synovial fluid at 6 and 12 months after ACL transection in untreated and repaired porcine knees. Our primary aim was to determine how the synovial fluid proteome ...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2019-02-16 | PXD012720 | Pride
Porcine Knee Synovial fluide Acl injury Ptoa 
GenomicsMacrophage Senescence Links ACL Injury to Posttraumatic Osteoarthritis and Muscle Atrophy
Macrophage Senescence Links ACL Injury to Posttraumatic Osteoarthritis and Muscle Atrophy
PRJNA1379624 | ENA
TranscriptomicsRNA-seq of synovial membranes from a preclinical model of post-traumatic knee osteoarthritis to evaluate the effects of corticosteroid treatment
Yorkshire pigs received untreated unilateral ACL transection through a medial arthrotomy (INJ, n=6), transection with immediate injection of 20mg triamcinolone acetonide (TRI, n=6) or no surgery (CON, n=6). Synovial membranes were harvested two weeks after the injury in the lateral knee joint compar...
ORGANISM(S): Sus scrofa 
2016-01-29 | E-MTAB-4294 | biostudies-arrayexpress
GenomicsMacrophage Senescence Links ACL Injury to Posttraumatic Osteoarthritis and Muscle Atrophy [scRNA-seq]
Macrophage Senescence Links ACL Injury to Posttraumatic Osteoarthritis and Muscle Atrophy [scRNA-seq]
PRJNA1379643 | ENA
ProteomicsProteomics Reveals Increased Periostin in Synovial Fluid from Canine and Human Anterior Cruciate Ligament Injury
Post-traumatic osteoarthritis (PTOA) is a common sequela to anterior cruciate ligament (ACL) injury in humans and dogs. Identification of conserved targets between species may hasten biomarker identification and therapeutic development. To identify differentially regulated synovial fluid (SF) protei...
ORGANISM(S): Homo sapiens (Human) Canis familiaris (Dog) (Canis lupus familiaris) 
2025-06-16 | PXD061915 | Pride
Canine Alpha-2-macroglobulin Proteomics Osteoarthritis Periostin Human Acl Lc-ms/ms 
ProteomicsProteomic analysis of synovial fluid identifies periostin as a biomarker for anterior cruciate ligament injury
Identification of novel synovial fluid biomarkers that can differentiate early changes following ACL injury from OA using tandem-mass-spectrometry
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-03-11 | MSV000083551 | MassIVE
ProteomicsSynovial fluid proteomics from serial aspiration of ACL injured knees identifies candidate biomarkers for osteoarthritis
Patients with anterior cruciate ligament (ACL) tears have a significantly increased risk for developing knee osteoarthritis. These injuries often result in a knee effusion in response to the injury. Early changes in these effusions could be informative regarding initial steps in the development of...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-06-23 | MSV000089716 | MassIVE
UnknownClinical outcomes after anterior cruciate ligament injury: panther symposium ACL injury clinical outcomes consensus group.
Not available
S-EPMC7429530 | biostudies-literature
TranscriptomicsMacrophage Senescence Links ACL Injury to Posttraumatic Osteoarthritis and Muscle Atrophy
Traumatic knee injury often leads to posttraumatic osteoarthritis (PTOA) and significant skeletal muscle atrophy and weakness, resulting in chronic disability. The current standard of care frequently fails to prevent musculoskeletal dysfunction, underscoring the need to identify therapeutically targ...
ORGANISM(S): Mus musculus 
2026-07-29 | GSE313473 | GEO
TranscriptomicsTranscript Expression Changes over Time-from-injury in Anterior Cruciate Ligament Tears: Implications for Reconstruction and Repair
The anterior cruciate ligament (ACL) is an essential stabilizer of the tibiofemoral articulation. ACL tears often lead to functional instability and are associated with an increased risk for osteoarthritis. The healing potential of the injured ACL is poorly understood and is considered to be limited...
ORGANISM(S): Homo sapiens 
2014-09-13 | E-GEOD-61385 | biostudies-arrayexpress
Sort   by:  
 Page size