Sort   by:  
 Page size 
ProteomicsProteome integral solubility alteration assay combined with multi-criteria decision-making analysis for developing adverse outcome pathways
To simplify chemical risk assessment, the adverse outcome pathway (AOP) method has arisen as a framework to predict the impact of chemical exposure on human and environmental health. The development of this predictive tool requires knowledge of the molecular interaction between chemicals and protein...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD033056 | Pride
Hepatocytes Bioactive compound Pollutants Proteome integral solubility alteration assay Tcdd Analytical hierarchy process Hepg2 
UnknownAOP-helpFinder webserver: a tool for comprehensive analysis of the literature to support adverse outcome pathways development.
Not available
S-EPMC8796376 | biostudies-literature
GenomicsAdverse outcome pathways of ionizing radiation investigated with multi-omics and benchmark dose modeling
Adverse outcome pathways of ionizing radiation investigated with multi-omics and benchmark dose modeling
PRJNA1082296 | ENA
UnknownAOP-DB: A database resource for the exploration of Adverse Outcome Pathways through integrated association networks.
Not available
S-EPMC6104822 | biostudies-literature
UnknownProviding Adverse Outcome Pathways from the AOP-Wiki in a Semantic Web Format to Increase Usability and Accessibility of the Content.
Not available
S-EPMC8978481 | biostudies-literature
TranscriptomicsA quantitative adverse outcome pathway for predicting medium-term lung function evolution after switching from combustible cigarettes to heated tobacco products
Adverse outcome pathways (AOP) contain summarizing sequences of key events (KE) relating toxicant exposures to specific adverse outcomes (AO) observed in exposed populations. Quantitative AOPs (qAOP) provide frameworks to assess AO risks based on KE quantification and the modeling of their relations...
ORGANISM(S): Homo sapiens 
2024-02-19 | E-MTAB-13344 | biostudies-arrayexpress
UnknownAOP-networkFinder-a versatile tool for the reconstruction and visualization of Adverse Outcome Pathway networks from AOP-Wiki.
Not available
S-EPMC11835234 | biostudies-literature
UnknownPutative adverse outcome pathways relevant to neurotoxicity.
Not available
S-EPMC5072123 | biostudies-literature
TranscriptomicsAdverse outcome pathways of ionizing radiation investigated with multi-omics and benchmark dose modeling
Background/Issue and Objectives: Health risks from chronic low dose radiation exposures encountered in environmental and occupational settings are uncertain. A key aspect to understanding health risks is precise and accurate modelling of the dose-response relationship. Benchmark dose (BMD) modeling ...
ORGANISM(S): Homo sapiens 
2025-02-28 | GSE260589 | GEO
UnknownSemantic characterization of adverse outcome pathways.
Not available
S-EPMC7393770 | biostudies-literature
Sort   by:  
 Page size