Aguirre John A JA

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Unknown (36)
Metabolomics (1)
Proteomics (1)

Organisms

Homo sapiens (1)
Mus musculus (1)

Repository

MetaboLights (1)
pride (1)

Technology Type

Mass spectrometry (1)
Mass Spectrometry (1)
Shotgun proteomics (1)

Instrument Platform

Liquid Chromatography MS - alternating - reverse phase (1)

Publication Date

2022 (2)

CHEBI ID

CHEBI:132542 (1)
CHEBI:132579 (1)
CHEBI:134242 (1)
CHEBI:134487 (1)
CHEBI:134587 (1)
CHEBI:137552 (1)
CHEBI:137590 (1)
CHEBI:140940 (1)
CHEBI:140946 (1)
CHEBI:140951 (1)
CHEBI:156118 (1)
CHEBI:16113 (1)
CHEBI:183249 (1)
CHEBI:183798 (1)
CHEBI:183799 (1)
CHEBI:183800 (1)
CHEBI:183804 (1)
CHEBI:64431 (1)
CHEBI:64446 (1)
CHEBI:64483 (1)
CHEBI:64516 (1)
CHEBI:64517 (1)
CHEBI:64521 (1)
CHEBI:64549 (1)
CHEBI:64559 (1)
CHEBI:64560 (1)
CHEBI:64561 (1)
CHEBI:64566 (1)
CHEBI:64568 (1)
CHEBI:65293 (1)

Metabolite Name

AcCa (12:0) (1)
CE (16:1) (1)
CE (18:0) (1)
CE (18:1) (1)
CE (18:2) (1)
CE (20:2) (1)
CE (20:4) (1)
Cer (d34:0)a.(d18:0/16:0) (1)
Cer (d34:0)b.(d16:0/18:0) (1)
Cer (d40:0).(d18:0/22:0) (1)
Cer (d40:1)b.(d18:1/22:0) (1)
Cer (d42:1)a.(d18:0/24:1) (1)
Cer (d42:1)b.(d18:1/24:0) (1)
Cer (d42:2)b.(d18:1/24:1) (1)
Cer (d44:2)a.(d18:1/26:1) (1)
Cer (d44:2)b.(d20:1/24:1) (1)
Cer (m34:0).(m18:0/16:0) (1)
Cer (m34:2).(m18:2/16:0) (1)
Cer (m36:2).(m18:2/18:0) (1)
Cer (m38:0).(m18:0/20:0) (1)
Cer (m38:2)b.(m18:2/20:0) (1)
Cholesterol.-H2O (1)
DAG (32:0).(30:0/FA16:0) (1)
DAG (36:2).(36:2/FA18:1) (1)
DAG (38:5).(38:5/FA18:1) (1)
FA (14:0) (1)
FA (17:1) (1)
FA (20:0) (1)
FA (22:4) (1)
GM3 (d36:1).(d18:1/18:0) (1)

Release Date

2021 (12)
2024 (6)
2025 (4)
2022 (4)
2018 (4)
2020 (3)
2023 (1)
2017 (1)
2016 (1)

Lab affiliation

Division of Radiation and Genome Stability, Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA Department of Radiation Oncology, Brigham and Women’s Hospital, Boston, MA 02115 (1)

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NCOA4-mediated ferritinophagy is a pancreatic cancer dependency via maintenance of iron bioavailability for iron-sulfur cluster proteins

Oncogenic KRAS rewires pancreatic ductal adenocarcinoma (PDAC) metabolism to promote dependence on autophagy and iron metabolism. NCOA4-mediated ferritinophagy links autophagy and iron metabolism as NCOA4 selectively targets ferritin, the cellular iron storage complex, via autophagy to the lysosome ...

ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse)

2022-08-17 | PXD033356 | Pride

NCOA4-Mediated Ferritinophagy Is a Pancreatic Cancer Dependency via Maintenance of Iron Bioavailability for Iron-Sulfur Cluster Proteins.

Not available

S-EPMC9437572 | biostudies-literature

The Bardet-Biedl protein Bbs1 controls photoreceptor outer segment protein and lipid composition

Summary

Primary cilia are key sensory organelles whose dysfunction leads to ciliopathy disorders such as Bardet-Biedl syndrome (BBS). Retinal degeneration is common in ciliopathies, since the outer segments (OSs) of photoreceptors are highly specialized primary cilia. BBS...

2022-02-18 | MTBLS4013 | MetaboLights

Hyperoxemia and excess oxygen use in early acute respiratory distress syndrome: insights from the LUNG SAFE study.

Not available

S-EPMC7110678 | biostudies-literature

Associations of Sex, Race, and Apolipoprotein E Alleles With Multiple Domains of Cognition Among Older Adults.

Not available

S-EPMC10352930 | biostudies-literature

Repurposed Antiviral Drugs for Covid-19 - Interim WHO Solidarity Trial Results.

Not available

S-EPMC7727327 | biostudies-literature

Identifying associations between diabetes and acute respiratory distress syndrome in patients with acute hypoxemic respiratory failure: an analysis of the LUNG SAFE database.

Not available