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TranscriptomicsAllele-specific Methylation of Human Placental Tissue
In this study, we screened human placental samples for allele-specific methylation and subsequently novel imprinted genes associated with these regions. We used reduced representation bisulfite sequencing to identify partially methylated CpG islands (CGIs) in the human placental genome. We were able...
ORGANISM(S): Homo sapiens 
2013-10-09 | E-GEOD-40955 | biostudies-arrayexpress
TranscriptomicsAllele-specific chromosome conformations induced by a transgene- and locus-dependent imprinting
A reporter transgene displayed parental imprinting in mouse embryos when positioned into the Itga6 gene. The strong lacZ pattern of expression scored in embryos inheriting the transgene from a male was not present when transmitted from a female. The transgene exhibited maternal allele-specific DNA ...
ORGANISM(S): Mus musculus 
2013-07-03 | E-GEOD-48148 | biostudies-arrayexpress
ProteomicsPolysomal profiling coupled to allele-specific proteomics reveals an EIF4H tranSNP allele possessing higher mRNA translation potential
To search for genetic sources of allele-specific mRNA translation, we leveraged heterozygous polymorphisms and variants present in the exome of HCT116-derived cell lines, computing allelic fractions in total and polysome-associated RNA from RNA-seq data. Allelic imbalance in polysomal RNA led us to ...
ORGANISM(S): Homo sapiens (Human) 
2026-09-16 | PXD063767 | Pride
Snps Allele-specific proteomics Allelic imbalance Mrna translation Eif4h 
GenomicsAllele specific MC-4C
Allele specific version of MC-4C
PRJEB31714 | ENA
TranscriptomicsDynamics of gene silencing during X inactivation using allele-specific RNA-Seq
Background: During early embryonic development, one of the two X chromosomes in mammalian female cells is inactivated to compensate for a potential imbalance in transcript levels with male cells containing a single X chromosome. We use mouse female Embryonic Stem Cells (ESCs) with nonrandom XCI and ...
ORGANISM(S): Mus musculus 
2015-06-15 | E-GEOD-60738 | biostudies-arrayexpress
TranscriptomicsAllele-specific expression and eQTL analysis in mouse adipose tissue
In this study we use RNAseq to explore allele specific expression (ASE) in adipose tissue of male and female F1 mice, produced from reciprocal crosses of C57BL/6J and DBA/2J strains. Comparison of the identified cis-eQTLs, to local-eQTLs, that were obtained from adipose tissue expression in two prev...
ORGANISM(S): Mus musculus 
2014-06-05 | E-GEOD-58239 | biostudies-arrayexpress
ProteomicsDessert banana vs plantain: characterization of allele specific protein isoforms that are correlated to the fruit maturation process
Dessert bananas have a soft texture and sweet taste at maturity. Plantain fruits belongs to Musa spp (AAB) and are known cooking bananas. This popular name is due to the fact that these fruits do keep a high amount of starch even after complete maturation and have a different flesh texture being not...
ORGANISM(S): Musa 
2018-01-22 | PXD005589 | Pride
Banana breeding Plantain Proteomic Allele specific Banana 
TranscriptomicsChromosome wide analysis of parental allele specific chromatin and DNA methylation in mouse
This SuperSeries is composed of the following subset Series: GSE26720: Chromosome wide analysis of parental allele specific chromatin and DNA methylation GSE26891: Chromosome wide analysis of parental allele specific chromatin and DNA methylation along mouse distal chr7 GSE26892: Chromosome wide ana...
ORGANISM(S): Mus musculus 
2011-03-31 | E-GEOD-26947 | biostudies-arrayexpress
ProteomicsA Novel QconCAT-Based Proteomics Method for Determining Allele-Specific Protein Expression (ASPE)
In the present study, we developed a novel targeted proteomics approach for quantification of allele-specific protein expression (ASPE) based on scheduled high resolution multiple reaction monitoring (sMRM-HR) with a heavy stable isotope-labeled quantitative concatamer (QconCAT) internal protein sta...
ORGANISM(S): Homo sapiens (Human) 
2018-08-28 | PXD008788 | Pride
Human Allele-specific protein expression Liver 
GenomicsAllelome.PRO A pipeline to define allele-specific genome features
We used RNA-seq data from mouse embryonic fibroblasts from F1 reciprocal crosses to determine a biologically relevant allelic ratio cutoff, and define for the first time an entire allelome. Furthermore, we show that Allelome.PRO detects differential enrichment of H3K4me3 over promoters from ChIP-seq...
ORGANISM(S): Mus musculus 
2015-08-03 | E-GEOD-69168 | biostudies-arrayexpress
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