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ProteomicsVESTIGIAL-LIKE 1 IS A SHARED TARGETABLE CANCER-PLACENTA ANTIGEN EXPRESSED BY PANCREATIC AND BASAL-LIKE BREAST CANCERS
Cytotoxic T lymphocyte (CTL)-based cancer immunotherapies have shown great promise for inducing clinical regression by targeting tumor-associated antigens (TAA). To expand the TAA landscape of pancreatic ductal adenocarcinoma (PDAC), we performed tandem mass spectrometry analysis of HLA class I-boun...
ORGANISM(S): Homo sapiens (Human) 
2020-10-19 | PXD018302 | Pride
Human Pdac Mhc 
ProteomicsAcetyl-CoA availability regulates neuronal metabolism, growth, and synaptic activity
The metabolite acetyl-CoA plays a central role in cellular metabolic homeostasis. As part of the secretory pathway, acetyl-CoA is imported into the endoplasmic reticulum (ER) by a membrane-bound transporter AT-1 (SLC33A1). AT-1 has been linked to peripheral neuropathy (heterozygous mutations), devel...
ORGANISM(S): Mus musculus (Mouse) 
2026-09-11 | PXD075949 | Pride
Metabolism Acetyl-coa Proteomics Neuron Mitochondria 
TranscriptomicsTranscription profiling of liver samples from Macaca fascicularis treated with varying doses of ciprofibrate for 4 or 15 days
Liver gene expression was examined in male cynomolgus monkeys treated with ciprofibrate (PPAR-alpha agonist) for 4 days at 400 mg/kg/day and treated for 15 days at 0, 3, 30, 150 or 400 mg/kg/day. The untreated control group were given only the vehicle (0.5% hydroxypropyl methylcellulose). Two anim...
ORGANISM(S): Macaca fascicularis 
2007-07-22 | E-GEOD-2853 | biostudies-arrayexpress
ProteomicsTMT-based total protein and phosphopeptide quantification of mouse brain with human Tau insert
The gut microbiome modulates metabolic and neurovascular processes implicated in Alzheimer’s disease and related dementias (ADRD), but the underlying mechanisms remain unclear. Here, we identify the bacterial metabolite imidazole propionate (ImP) as a modifier of ADRD pathology. In a cohort of 1,196...
ORGANISM(S): Mus musculus (Mouse) 
2026-08-18 | PXD077817 | Pride
Tmtpro Amyloid Phosphoproteomics Alzheimer 
UnknownSeven-year follow-up assessment of cardiac function in NSABP B-31, a randomized trial comparing doxorubicin and cyclophosphamide followed by paclitaxel (ACP) with ACP plus trastuzumab as adjuvant therapy for patients with node-positive, human epidermal growth factor receptor 2-positive breast cancer.
Not available
S-EPMC3478574 | biostudies-literature
UnknownCapecitabine and oxaliplatin in the preoperative multimodality treatment of rectal cancer: surgical end points from National Surgical Adjuvant Breast and Bowel Project trial R-04.
Not available
S-EPMC4050205 | biostudies-literature
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