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MetabolomicsHypoxia promotes osteogenesis via regulating the acetyl-CoA-mediated mito-nuclear communication.
Not available
ORGANISM(S): Mus musculus 
ST002242 | MetabolomicsWorkbench
Metabolomics2,3,7,8 -Tetrachlorodibenzo-p-dioxin Mediated Effects on Hepatic Coenzyme A (CoA) and Acetyl-CoA Levels (part-I)
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ORGANISM(S): Mus musculus 
ST001376 | MetabolomicsWorkbench
MetabolomicsPlasmodium falciparum metabolomics as a result of treatment with putative acetyl-CoA synthetase inhibitors
Not available
ORGANISM(S): Plasmodium falciparum 
ST001660 | MetabolomicsWorkbench
Metabolomics2,3,7,8 -Tetrachlorodibenzo-p-dioxin Mediated Effects on Hepatic Coenzyme A (CoA) and Acetyl-CoA Levels (part-II)
Not available
ORGANISM(S): Mus musculus 
ST001379 | MetabolomicsWorkbench
MetabolomicsMulti-omics analysis delineates the distinct functions of sub-cellular acetyl-CoA pools in Toxoplasma gondii
Not available
ORGANISM(S): Toxoplasma gondii 
ST001304 | MetabolomicsWorkbench
TranscriptomicsEngineering acetyl-CoA supply: Functional expression of a bacterial pyruvate-dehydrogenase complex in the cytosol of Saccharomyces cerevisiae
The energetic (ATP) cost of biochemical pathways critically determines the maximum yield of metabolites of vital or commercial relevance. Cytosolic acetyl-CoA is a key precursor for biosynthesis in eukaryotes and for many industrially relevant product pathways that have been introduced into Saccharo...
ORGANISM(S): Saccharomyces cerevisiae 
2014-11-04 | E-GEOD-59814 | biostudies-arrayexpress
ProteomicsLinking acetyl-CoA labelling and histone acetylation dynamics for accurate determination of acetylation rates via ordinary differential equations
To study complex biological systems, multi-omics methods have become an important tool. They integrate data from multiple biological layers, such as the metabolome and the proteome, to gain better insights of the processes happening. However, challenges remain both in sample preparation for measurem...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD051487 | Pride
Human Lc-msms Acetylcoa Ptm Histone Acetylation Hek93t 
ProteomicsPDHE1α, PARylation, Acetyl-CoA, Acetylation, Histones, DNA damage repair
Chromatin relaxation is a prerequisite step that allows the DNA repair machinery to access double-strand breaks (DSBs), and local histones around the DNA breaks suffer from prompt acetylation changes. However, an intriguing question remains as to where the large demands of acetyl-CoA is precisely pr...
ORGANISM(S): Homo sapiens (Human) 
2023-07-27 | PXD040676 | Pride
Pdhe1α Acetyl-coa Dna damage repair Parylation Histones Acetylation 
TranscriptomicsReplacement of the Saccharomyces cerevisiae acetyl-CoA synthetases by alternative pathways for cytosolic acetyl-CoA synthesis
Cytosolic acetyl-coenzyme A is a precursor for many biotechnologically relevant compounds produced by Saccharomyces cerevisiae. In this yeast, cytosolic acetyl-CoA synthesis and growth strictly depend on expression of either the Acs1 or Acs2 isoenzyme of acetyl-CoA synthetase (ACS). Since hydrolysis...
ORGANISM(S): Saccharomyces cerevisiae 
2013-11-21 | E-GEOD-47983 | biostudies-arrayexpress
ProteomicsElucidating the diverse roles of acetyl-CoA in the cytosol and mitochondrion of Toxoplasma gondii
Acetyl-CoA is a key metabolite in all organisms, implicated in transcriptional regulation, post-translational modification as well as fuelling the TCA cycle and the synthesis and elongation of fatty acids. The obligate intracellular parasite Toxoplasma gondii possesses two enzymes which produce acet...
ORGANISM(S): Toxoplasma gondii RH 
2020-05-07 | PXD016133 | Pride
Metabolism Acetylome Acetyl-coa Toxoplasma gondii Nanolc-ms/ms 
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