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TranscriptomicsAortic arch profiling of Apoe knockout mice
Aortic arch profiling of Apoe-/- mice fed a high fat diet (HFD, Harlan Teklad 88137, 21% fat, 0.15% cholesterol) starting at 8 weeks of age for 8, 16, and 24 weeks. B6 mice fed HFD for 16 weeks starting at 8 weeks of age were used as controls. Apoe-/- mice were fed a high fat diet (HFD, Harlan Tekl...
ORGANISM(S): Mus musculus 
2010-06-22 | E-GEOD-18443 | biostudies-arrayexpress
TranscriptomicsAortic arch profiling of Ldlr knockout mice with human CETP transgene
Aortic arch profiling of Ldlr-/- huCETP transgenic mice fed a low fat, cholesterol-containing western diet (LFWD, 9% fat, 0.15% cholesterol) starting at 8 weeks of age for 4, 8, 12, and 16 weeks. Ldlr-/- huCETP transgenic mice were fed a low fat, cholesterol-containing western diet (LFWD, 9% fat, ...
ORGANISM(S): Mus musculus 
2010-06-22 | E-GEOD-18442 | biostudies-arrayexpress
TranscriptomicsRNA-seq analysis of branchial arches and outflow tract of the mouse embryo at E10.5 and E11.5
The aim of the study was to identify the key genes responsible for the remodelling of aortic arches into mature heart circulation.
ORGANISM(S): Mus musculus 
2017-09-25 | E-MTAB-5394 | biostudies-arrayexpress
TranscriptomicsscRNA-seq of aortic arches from smooth muscle cell–specific Hif1a knockout and control mice with atherosclerosis
Smooth muscle cells (SMCs) undergo phenotypic switching during atherosclerosis and give rise to a large fraction of plaque cells. To investigate the role of hypoxia-inducible factor 1α (HIF1α) signaling in SMC behaviour during atherogenesis, we used mice in which Hif1a is conditionally deleted in li...
ORGANISM(S): Mus musculus 
2026-06-21 | E-MTAB-17142 | biostudies-arrayexpress
ProteomicsWild-type and O/E uPA in mouse aortic arches_PROTOMAP
Aortic arches from WT and overexpression of uPA were extracted and their proteome was processed and subjected to PROTOMAP analysis.
ORGANISM(S): Mus musculus (Mouse) 
2020-08-10 | PXD020406 | Pride
Protomap Aortic arches Upa 
TranscriptomicsRNA-seq analysis of the first branchial arch of the mouse embryos at E10.5 and E11.5
The aim of the study was to identify the key genes responsible for the remodelling of aortic arches into mature heart circulation.
ORGANISM(S): Mus musculus 
2020-01-06 | E-MTAB-7963 | biostudies-arrayexpress
TranscriptomicsMicroRNA profiling by array of Sus scrofa endothelial cells isolated from the athero-protective descending thoracic aorta and the athero-susceptible aortic arch
This study investigates the regional expression profiles of microRNAs (miRNAs) in endothelial cells isolated from the athero-protective descending thoracic aorta (DT) and from the athero-susceptible aortic arch (AA) in a swine model. Seven 2-channel assays comparing DT samples to AA samples were per...
ORGANISM(S): Sus scrofa 
2010-07-16 | E-CBIL-46 | biostudies-arrayexpress
TranscriptomicsEmbryonic transcriptional program for remodeling of the heart circulation
The branchial arches house bilaterally symmetric embryonic vessels, called aortic arches which connect the heart to the embryonic circulation. These undergo a significant remodelling to form the final structure of the great arteries of the neck and head. This study compared the transcriptomes of E11...
ORGANISM(S): Mus musculus 
2026-08-25 | E-MTAB-5382 | biostudies-arrayexpress
TranscriptomicsIdentification and validation of causal genes for atherosclerosis in mice
Identification of causal genes for atherosclerosis in a segregating mouse population and validation via single-gene knockout and plaque progression mouse models. This SuperSeries is composed of the following subset Series: GSE18442: Aortic arch profiling of Ldlr knockout mice with human CETP transg...
ORGANISM(S): Mus musculus 
2010-06-23 | E-GEOD-18479 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNA sequencing experiment of aortic arch and root samples from mice with rHDL and PS@rHDL treatment
The experiment was performed by using Apoe-/- mice fed on a high-fat, high-cholesterol diet (Western diet, WD) for either 6 weeks. The samples were collected from aortic arch and root of two different groups of mice: one treated with rHDL (reconstituted HDL nanoparticles), and the other with PS@rHDL...
ORGANISM(S): Mus musculus 
2024-08-08 | E-MTAB-14252 | biostudies-arrayexpress
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