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MetabolomicsLC-HRMS Metabolomics for Untargeted Diagnostic Screening in Clinical Laboratories: A Feasibility Study
Today's high-resolution mass spectrometers (HRMS) allow bioanalysts to perform untargeted/global determinations that can reveal unexpected compounds or concentrations in a patient’s sample. This could be performed for preliminary diagnosis attempts when usual diagnostic processes and targeted ...
2019-06-06 | MTBLS476 | MetaboLights
UnknownGenetic aberrations in iPSCs are introduced by a transient G1/S cell cycle checkpoint deficiency.
Not available
S-EPMC6954237 | biostudies-literature
TranscriptomicsCell cycle-regulated gene expression in tobacco cells
Tobacco BY-2 cells can be highly synchronized by treatment with an inhibitor of DNA synthesis, aphidicolin. For comprehensive understanding of cell cycle-regulated gene expression in tobacco, microarray analysis was conducted in synchronized cultures of BY-2 cells. Cells were treated with aphidicoli...
ORGANISM(S): Nicotiana tabacum 
2010-05-22 | E-GEOD-14250 | biostudies-arrayexpress
TranscriptomicsKinetochores coordinate pericentromeric cohesion and early DNA replication by Cdc7-Dbf4 kinase recruitment
Centromeres play several important roles in ensuring proper chromosome segregation. Not only do they promote kinetochore assembly for microtubule attachment, but they also support robust sister chromatid cohesion at pericentromeres and facilitate replication of centromeric DNA early in S phase. Howe...
ORGANISM(S): Saccharomyces cerevisiae 
2013-06-06 | E-GEOD-41982 | biostudies-arrayexpress
UnknownA new class of glutathione S-transferase from the hepatopancreas of the red sea bream Pagrus major.
Not available
S-EPMC1186719 | biostudies-literature
ProteomicsCysteine-targeted proteomics analysis
The protein cysteine residue is one of the amino acids most susceptible to oxidative modifications, frequently caused by oxidative stress. Several applications have enabled cysteine-targeted proteomics analysis with simultaneous detection and quantitation. In this study, we employed a quantitative a...
ORGANISM(S): Homo sapiens (Human) 
2016-07-18 | PXD004303 | Pride
Hek293t Iodotmt6plex 
TranscriptomicsArabidopsis Me-0 vs tetraploid Col
To investigate gene expression differences related to the regulation of stomatal aperture between two Arabidopsis accessions, Me-0 and tetraploid Col, we performed microarray analysis on guard cell protoplasts from these two accessions. We identified 1,777 probes as up-regulated and 1,706 probes as ...
ORGANISM(S): Arabidopsis thaliana 
2016-01-14 | E-GEOD-71914 | biostudies-arrayexpress
UnknownLysine-specific demethylase-2 is distinctively involved in brown and beige adipogenic differentiation.
Not available
S-EPMC6436657 | biostudies-literature
UnknownNicotinamide mononucleotide adenylyltransferase expression in mitochondrial matrix delays Wallerian degeneration.
Not available
S-EPMC6665489 | biostudies-literature
UnknownUrinary Potassium Excretion and Renal and Cardiovascular Complications in Patients with Type 2 Diabetes and Normal Renal Function.
Not available
S-EPMC4670758 | biostudies-literature
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