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ProteomicsSpecies identification of archaeological skin objects from Danish bogs
Denmark has an extraordinarily large and well-preserved collection of archaeological skin garments found in peat bogs, dated to approximately 920 BC - AD 775. These objects provide not only the possibility to study prehistoric skin costume and technologies, but also to investigate the animal species...
ORGANISM(S): Bos taurus (Bovine) Ovis aries Capra hircus (Goat) 
2014-07-29 | PXD001029 | Pride
Archaeological skin objects from bogs Archaeology Ancient proteins 
ProteomicsProteomic invetsigations of archaeological ceramics from Tell Khaiber
This project looks at archaeological ceramics from Tell Khaiber (Sealand Dynasty, mid-second millenium BCE, Southern Iraq) and analyses the proteins absorbed in them determining resource use.
ORGANISM(S): Glycine max x Glycine soja 
2022-08-09 | PXD022507 | Pride
Archaeological ceramics Tell khaiber Paleoproteomics Ancient diet Lc-ms/ms 
ProteomicsA simplified sample preparation for hair and skin proteins towards the application of archaeological fur and leather
Traditional protocols for proteomics analysis usually start by extracting or solubilizing the proteins from their substrates. This step can be challenging for archaeological proteins, when they are heavily contaminated or decayed. The remains of animal fur/leather objects from the singer’s burial of...
ORGANISM(S): Bos taurus (Bovine) Ovis aries 
2023-01-17 | PXD036745 | Pride
Collagen Archaeological burial Keratin Proteomics 
ProteomicsPalaeoproteomics of archaeological shell beads
In this project we have applied palaeoproteomics to study archaeological shell beads dating back to the beginning of the 7th mill. cal BCE and recovered from a prehistoric site in Jordan (Ba'ja). These beads were made of mollusc shells and were of unknown origin, but suspected to be made of larger b...
ORGANISM(S): Mollusca 
2024-11-04 | PXD041082 | Pride
Archaeological shells Mollusc shells Ancient proteins Palaeoproteomics Lc-ms/ms 
ProteomicsA unified protocol for simultaneous extraction of DNA and proteins from archaeological dental calculus
Archaeological materials are a finite resource, and efforts should be made to minimize destructive analyses. This can be achieved by using protocols combining extraction of several lines of evidence, which decreases the material needed for analyses while maximizing the information yield. Archaeologi...
ORGANISM(S): Homo sapiens (Human) 
2020-04-27 | PXD015817 | Pride
Ancient dna  palaeoproteomics  oral microbiome  dental plaque  metagenomics 
ProteomicsTaphonomy and Negative Results: An Integrated Approach to Ceramic-bound Protein Residue Analysis
Despite the growing body of evidence demonstrating that proteins can survive for thousands to even millions of years in selected contexts, there are relatively few examples of the successful recovery and identification of archaeological protein residues from ceramic artifacts. Claims of positive res...
ORGANISM(S): Bos taurus (Bovine) 
2018-12-24 | PXD009431 | Pride
Taphonomy Lc-ms Archaeological proteins Ceramics 
ProteomicsMilking it? Assessing the degradation of ancient milk proteomes
The origins, prevalence and nature of dairying have been long debated by archaeologists. Within the last decade, new advances in high-resolution mass spectrometry have allowed for the direct detection of milk proteins from archaeological remains, including ceramics, dental calculus, and preserved da...
ORGANISM(S): Homo sapiens (Human) 
2021-08-05 | PXD022368 | Pride
Milk Authentication Palaeoproteomics Deamidation 
ProteomicsSuccessive protein extraction using hydroxylamine to increase the depth of proteome coverage in fresh, forensic and archaeological bones
Proteomics is continually being applied to a wider range of applications, now including the analysis of archaeological samples and anatomical specimens, in particular, collagen-containing tissues such as bones and teeth. Here we present the application of a chemi-cal digestion-based proteomics sampl...
ORGANISM(S): Bos taurus (Bovine) Homo sapiens (Human) 
2024-03-28 | PXD046969 | Pride
Hydroxylamine Collagen Archaeology Chemical digestion 
ProteomicsTaxonomic identification of bone fragments in resin-embedded sediment blocks through palaeoproteomics
Identifying the taxonomy of bone fragments in resin-embedded archaeological sediment blocks can provide information about our past at a microstratigraphic resolution. Here, we first explore the effects of resin impregnation on modern bones, and find minimal effects on taxonomic identifications, but ...
ORGANISM(S): Bos taurus (Bovine) Pecora Caprinae Ursus arctos (Brown bear) (Grizzly bear) Canis lupus Ursus Bovinae Equus caballus (Horse) 
2025-09-02 | PXD061447 | Pride
Palaeoproteomics  archaeology  bone  pleistocene  resin 
ProteomicsPoor preservation of antibodies in archaeological human bone and dentine
The growth of proteomics-based methods in archaeology prompted an investigation of the survival of non-collagenous proteins, specifically immunoglobulin G (IgG), in archaeological human bone and dentine. Over a decade ago reports were published on extracted, immunoreactive archaeological IgG, and th...
ORGANISM(S): Homo sapiens (Human) 
2016-02-08 | PXD002295 | Pride
Human Dentine Antibodies Bone Immunoglobulin Lc-ms/ms 
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