Sort   by:  
 Page size 
ProteomicsRNAseq and quantitative proteomic analysis of Dictyostelium knock-out cells lacking the core autophagy proteins ATG9 and/or ATG16
Autophagy is an evolutionary ancient mechanism that sequesters substrates for degradation within autolysosomes. The process is driven by many autophagy-related (ATG) proteins, including the core members ATG9 and ATG16. Here, we applied RNAseq and tandem mass tag (TMT) proteomic approaches to identif...
ORGANISM(S): Dictyostelium discoideum (Slime mold) 
2021-06-15 | PXD023730 | Pride
Atg9 Rnaseq Parallel reaction monitoring (prm) Tandem mass tag (tmt) Autophagy Proteome Atg16 Dictyostelium discoideum 
ProteomicsProteasomes of autophagy-deficient cells exhibit changes in associated regulatory proteins in conjunction with a dramatic decrease in activity
To identify possible differences in proteasome-associated proteins, we generated AX2 wild-type and ATG16¯ cells expressing the GFP-tagged 20S proteasomal subunit PSMA4 and performed co-immunoprecipitation experiments followed by mass spectrometric analysis.
ORGANISM(S): Dictyostelium discoideum (Slime mold) 
2023-07-20 | PXD039713 | Pride
Ubiquitin proteasome system (ups) Dictyostelium Autophagy Atg16 
GenomicsRNAseq and quantitative proteomic analysis of Dictyostelium knock-out cells lacking the core autophagy proteins ATG9 and/or ATG16
RNAseq and quantitative proteomic analysis of Dictyostelium knock-out cells lacking the core autophagy proteins ATG9 and/or ATG16
PRJNA680492 | ENA
UnknownDimeric coiled-coil structure of Saccharomyces cerevisiae Atg16 and its functional significance in autophagy.
Not available
S-EPMC2801276 | biostudies-literature
TranscriptomicsRNAseq and quantitative proteomic analysis of Dictyostelium knock-out cells lacking the core autophagy proteins ATG9 and/or ATG16
Purpose: Global survey of the transcriptome and comparison to the proteome in autophagy-deficient strains of D. discoideum. Results: Our RNAseq analysis of ATG9‾, ATG16‾ and ATG9‾/16‾ cells revealed major transcriptional changes in a large number of genes in comparison to AX2. Conclusions: Our study...
ORGANISM(S): Dictyostelium discoideum 
2021-05-19 | GSE162070 | GEO
UnknownMembrane Binding and Homodimerization of Atg16 Via Two Distinct Protein Regions is Essential for Autophagy in Yeast.
Not available
S-EPMC7924733 | biostudies-literature
UnknownMechanism and functions of membrane binding by the Atg5-Atg12/Atg16 complex during autophagosome formation.
Not available
S-EPMC3501226 | biostudies-literature
UnknownThe phenotypes of ATG9, ATG16 and ATG9/16 knock-out mutants imply autophagy-dependent and -independent functions.
Not available
S-EPMC4422124 | biostudies-literature
UnknownCoiled-coil-mediated dimerization of Atg16 is required for binding to the PROPPIN Atg21.
Not available
S-EPMC10688262 | biostudies-literature
UnknownCrystallization of the Atg12-Atg5 conjugate bound to Atg16 by the free-interface diffusion method.
Not available
S-EPMC2394807 | biostudies-literature
Sort   by:  
 Page size