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Sister chromatid exchanges (SCEs) are a product of joint DNA molecules resolution, and are considered to require homologous recombination (HR). Canonical HR factors BRCA1, BRCA2 and RAD51 were indeed essential for SCE induction in response to irradiation-induced DNA breaks. By contrast, replication-...
ORGANISM(S): Xenopus laevis (African clawed frog) 
2023-03-11 | PXD028670 | Pride
The Septation Initiation Network (SIN) controls cytokinesis in fission yeast. This model uses CDK activity levels as control nodes to simutate SIN related events throughout different stages of the cell cycle. This model was optimized using single knock-out experiments and has made in silico predicti...
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