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ProteomicsIntegrative proteo-genomic profiling uncovers key biomarkers of lapatinib resistance in HER2-positive breast cancer
To understand the transcriptomic, genomic and proteomics changes between HER2 overexpressingcells and those that have become resistant to lapatinib
ORGANISM(S): Homo sapiens (Human) 
2025-11-17 | PXD056848 | Pride
3d Chromatin Proteomics Epigenetics Resistance Her2 Lc-ms/ms 
ProteomicsDeepMRM: targeted proteomics data interpretation package with deep learning-based object detection
LC-MRM-MS/MS data of 66 Pancreatic ductal adenocarcinoma patients. Includes peak list files (.mzML), quantification results (.tsv) and raw files (.d) of the three replicate data of all patients.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-07-19 | MSV000089914 | MassIVE
ProteomicsProteomic and pathway profiling of four Breast Cancer cell lines exosomes
Biomarker discovery in breast cancer (BC) is a clinical need for therapeutics and non-invasive diagnostics. In a single study, we provide a comparative differential proteomic profile of four invasion, metastasis, angiogenesis and drug resistance. Exosome proteome profile reflects their different BC ...
ORGANISM(S): Homo sapiens (Human) 
2024-10-17 | PXD024300 | Pride
Biomarker discovery Breast cancer Exosomes Differentially-expressed proteins Proteomic profile 
ProteomicsThe branched-chain amino acid transporter AAT10.2 of Trypanosoma brucei is regulated by substrate availability
A phosphoproteome analysis of procyclic form T. brucei revealed many amino acid transporters (AATs) of the amino acid/auxin permease (AAAP) family with phosphorylated residues exclusively in their hydrophilic N-terminal domain. AAT10.2, which contained multiple phosphorylated residues, was further c...
ORGANISM(S): Trypanosoma brucei 
2026-09-14 | PXD079824 | Pride
Phosphoproteomics Amino acid Branched-chain amino acids Transport Parasite Substrate specificity Tb927.8.8300 
ProteomicsRadioproteomics stratifies molecular response to antifibrotic treatment in pulmonary fibrosis
Antifibrotic therapy with nintedanib is the clinical mainstay in the treatment of progressive fibrosing interstitial lung disease (ILD). High-dimensional medical image analysis, known as radiomics, provides quantitative insights into organ-scale pathophysiology, generating digital disease fingerprin...
ORGANISM(S): Mus musculus (Mouse) 
2024-10-17 | PXD052594 | Pride
Interstitial lung disease Radiomics Proteomics Multiomics Imaging Lung fibrosis Nintedanib 
Proteomics,MultiomicsDIA-Umpire: comprehensive computational framework for data independent acquisition proteomics
This dataset consists of 44 raw MS files, comprising 27 DIA (SWATH) and 15 DDA runs on a TripleTOF 5600 and of two raw mass spectrometry files acquired on a Q Exactive. The composition of the dataset is described in the manuscript by Tsou et al., titled: "DIA-Umpire: comprehensive computational fra...
ORGANISM(S): Escherichia Coli (ncbitaxon:562) Homo Sapiens (ncbitaxon:9606) 
2017-04-27 | MSV000081023 | MassIVE
ProteomicsCPTAC CCRCC Discovery Study - DIA Proteome
This is a supplementary study to the CPTAC CCRCC Discovery Study - Proteome. Unlabeled, digested peptide material from individual tissue samples (ccRCC and NAT) was spiked with index Retention Time (iRT) peptides (Biognosys) and subjected to data-independent acquisition (DIA) analysis. Kidney cance...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-10-04 | MSV000093041 | MassIVE
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