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Acephalic spermatozoa syndrome is severe teratozoospermia, displaying the separation of the sperm head and tail. In 2015, we first reported that genetic ablation of SPATA6 results in the separation of sperm head and tail. Here, we focus on a co-chaperone protein BAG5 that interacts with SPATA6 and e...
ORGANISM(S): Mus musculus (Mouse) 
2023-11-14 | PXD042965 | Pride
Molecular chaperones are critical to maintaining intracellular proteostasis and have been shown to have a protective role against alpha-synuclein mediated toxicity. Co-chaperone proteins regulate the activity of molecular chaperones and connect the chaperone network to protein degradation and cell d...
ORGANISM(S): Homo sapiens (Human) 
2020-08-05 | PXD019473 | Pride
Genomics
BAG5
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