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ProteomicsIdentification of neoantigens in oesophageal adenocarcinoma
We present data from tissues of seven oesophageal adenocarcinomas of CD4 and CD8 T cell epitopes eluted from the cell surface using mass spectrometry (immunopeptidomics) of presented HLA bound peptides.This dataset forms part of the publication:Nicholas, B., Bailey, A., McCann, K.J., Wood, O., Walke...
ORGANISM(S): Homo sapiens (Human) 
2022-09-27 | PXD031108 | Pride
Human Oesophageal adenocarcinoma Immunopeptidome Hla 
UnknownBayesian reconstruction of P(r) directly from two-dimensional detector images via a Markov chain Monte Carlo method.
Not available
S-EPMC3627411 | biostudies-literature
TranscriptomicsAdvancing systemic toxicity risk assessment: Evaluation of a NAM-based toolbox approach
High throughput transcriptomics using the TempO-Seq (TM) platform for dose response modelling of 3 different cell lines treated with multiple compounds as part of a study to generate a toolbox and workflow for non-animal safety assessments. The data generated here was produced as one part of a toolb...
ORGANISM(S): Homo sapiens 
2025-09-15 | E-MTAB-15266 | biostudies-arrayexpress
ProteomicsOesophageal adenocarcinoma global proteomes
We present data of global proteomes for oesophageal adenocarcinoma and for normal adjacent tissue from seven donors.
ORGANISM(S): Homo sapiens (Human) 
2024-12-17 | PXD054428 | Pride
Human oesophageal adenocarcinoma 
ProteomicsImmunopeptidomics guided identification of neoantigens in non-small cell lung cancer
Discovery of tumour specific peptides (neoantigens) generating target specific personalised T cell therapies is difficult because of the complex relationship between genetic mutations and neoantigen presentation. Studies predicting neoantigens have a 5% success rate, and direct observations of neoan...
ORGANISM(S): Homo sapiens (Human) 
2026-07-03 | PXD028990 | Pride
Cancer Hla Lung Neoantigen Peptidome 
ProteomicsNon-small cell lung cancer global proteomics
We present data of global proteomes for non-small cell lung cancer for squamous cell and adenocarcinoma, and for normal adjacent tissue.
ORGANISM(S): Homo sapiens (Human) 
2024-12-17 | PXD054390 | Pride
Human lung cancer global proteome 
TranscriptomicsAn Advancement in Developmental and Reproductive Toxicity (DART) Risk Assessment: Evaluation of a Bioactivity and Exposure-Based NAM Toolbox
High throughput transcriptomics using the TempO-Seq (TM) platform for dose response modelling of 3 different cell lines treated with multiple compounds as part of a study to generate a toolbox and workflow for non-animal safety assessments. The data generated here was produced as one part of a toolb...
ORGANISM(S): Homo sapiens 
2025-09-15 | E-MTAB-15274 | biostudies-arrayexpress
ProteomicsImmunopeptidomics of ex-vivo tissues to identify T cell vaccine candidates for influenza
We present data comparing an immortal macrophage-like cell lines with ex-vivo infected lung tissues as the presentation models of direct observation of CD4 and CD8 T cell epitopes eluted from the cell surface using mass spectrometry (immunopeptidomics) of presented HLA bound peptides.
ORGANISM(S): Homo sapiens (Human) 
2022-01-13 | PXD022884 | Pride
Hla Influenza Lung Dendritic cell Peptidome 
ProteomicsIdentification of sensitiser modified HLA-peptides presented by keratinocytes
Skin sensitisation following the covalent modification of proteins by low molecular weight chemicals (haptenation) is mediated by cytotoxic T lymphocyte (CTL) recognition of human leukocyte antigen molecules (HLA) presented on the surface of almost all nucleated cells. There are three nonmutually ex...
ORGANISM(S): Homo sapiens (Human) 
2021-01-04 | PXD021373 | Pride
Human Keratinocytes Hla Dncb Peptidome 
ProteomicsImmunopeptidomics of a brain tumour cell line to identify HLA presented Zika peptides
We present data of a brain tumour cell line (USP7) infected with Zika virus (Strain: BeH819966, GenBank: KU365779.1) to identify CD8 T cell epitopes eluted from the cell surface using mass spectrometry (immunopeptidomics) of presented HLA bound Zika peptides.
ORGANISM(S): Homo sapiens (Human) 
2025-11-10 | PXD037627 | Pride
Hla Brain Zika Peptidome 
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