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ProteomicsIdentification of sensitiser modified HLA-peptides presented by keratinocytes
Skin sensitisation following the covalent modification of proteins by low molecular weight chemicals (haptenation) is mediated by cytotoxic T lymphocyte (CTL) recognition of human leukocyte antigen molecules (HLA) presented on the surface of almost all nucleated cells. There are three nonmutually ex...
ORGANISM(S): Homo sapiens (Human) 
2021-01-04 | PXD021373 | Pride
Human Keratinocytes Hla Dncb Peptidome 
TranscriptomicsGene expression changes by 2,4-dinitrochlorobenzene in human bulge-derived keratinocytes
In the epidermis, keratinocytes are involved in physical and first-line immune protection of the host. In this work, we analyzed molecular responses after the addition of contact sensitizers, 2,4-dinitrochlorobenzene (DNCB) using cultured human keratinocytes from the bulge region of a plucked hair f...
ORGANISM(S): Homo sapiens 
2010-04-09 | E-GEOD-14838 | biostudies-arrayexpress
GenomicsRNASeq of blood by Mesenchymal stem cells treatment on DNCB induced mice model
RNASeq of blood by Mesenchymal stem cells treatment on DNCB induced mice model
PRJNA861127 | ENA
GenomicsExpression data for mouse skin-in atopy DNCB model
Expression data for mouse skin-in atopy DNCB model
PRJNA801349 | ENA
GenomicsRNASeq of skin tissues by Mesenchymal stem cells treatment on DNCB induced mice model
RNASeq of skin tissues by Mesenchymal stem cells treatment on DNCB induced mice model
PRJNA862133 | ENA
TranscriptomicsRNASeq of blood by Mesenchymal stem cells treatment on DNCB induced mice model
Evaluate the therapeutic effects of different delivery route of MSC treantment in DNCB induced atopic dermatitis mice model.
ORGANISM(S): Mus 
2023-05-01 | GSE209517 | GEO
TranscriptomicsRNASeq of skin tissues by Mesenchymal stem cells treatment on DNCB induced mice model
Evaluate the therapeutic effects of different delivery route of MSC treantment in DNCB induced atopic dermatitis mice model.
ORGANISM(S): Mus musculus 
2023-05-01 | GSE209704 | GEO
UnknownSelective activation of TRPA1 ion channels by nitrobenzene skin sensitizers DNFB and DNCB.
Not available
S-EPMC8800105 | biostudies-literature
UnknownEstablishment and Characterization of Mild Atopic Dermatitis in the DNCB-Induced Mouse Model.
Not available
S-EPMC10418750 | biostudies-literature
TranscriptomicsChemical allergen-induced perturbations of the mouse lymph node DNA methylome
Epigenetic regulation of gene expression plays a pivotal role in the orchestration of immune responses and may determine the vigor, quality, or longevity of such responses. Chemical allergens can be divided into two categories: skin sensitizing chemicals associated with allergic contact dermatitis, ...
ORGANISM(S): Mus musculus 
2014-02-07 | E-GEOD-54768 | biostudies-arrayexpress
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