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ProteomicsProteomics from centrosome-enriched fractions of Jurkat E6-1 human T cells, human embryonic kidney 293 cells, resting human T lymphoblasts and activated human T lymphoblasts
Centrosome-enriched fractions of Jurkat E6-1 human T cells (JK), human embryonic kidney (HEK) 293 cells, resting human T lymphoblasts (LT CTRL) and activated human T lymphoblasts (LT ACT), with one biological replicate for each condition, were analysed by label-free LC-MS/MS. For further details, re...
ORGANISM(S): Homo sapiens (Human) 
2025-12-18 | PXD063199 | Pride
Hek T lymphoblasts Jurkat Post-translational modifications Human Itraq Lc-ms/ms 
ProteomicsSMARCA4 Phosphorilation inhibition
Cyclin-Dependent Kinase 9 (CDK9) as part of the PTEFb complex promotes transcriptional elongation and high-level gene expression. We now report that, paradoxically, CDK9 is also essential for maintaining gene silencing at heterochromatic loci. Through a live cell screen, we discovered that CDK9 inhi...
ORGANISM(S): Homo sapiens (Human) 
2023-06-13 | PXD008040 | Pride
Phosphoproteomics Colon cancer cells Lc-ms/ms 
ProteomicsSMARCA4_Phosphopeptide
Cyclin-Dependent Kinase 9 (CDK9) as part of the PTEFb complex promotes transcriptional elongation by promoting RNAPII pause release. We now report that, paradoxically, CDK9 is also essential for maintaining gene silencing at heterochromatic loci. Through a live cell screen, we discovered that CDK9 i...
ORGANISM(S): Homo sapiens (Human) 
2020-05-26 | PXD009573 | Pride
Cdk9 Brg1 Epigenetics 
UnknowniSanXoT: A standalone application for the integrative analysis of mass spectrometry-based quantitative proteomics data.
Not available
S-EPMC10792623 | biostudies-literature
ProteomicsProteomics from centrosome-enriched fractions from resting and activated T lymphoblasts
Human resting and activated T lymphoblast (LT CTRL and LT ACT) centrosome-enriched subcellular fractions from LT CTRL and LT ACT were prepared as analysed by multiplexed quantitative proteomics and LC-MS/MS. Samples from different donors were pooled after first lysis. For further details, refer to r...
ORGANISM(S): Homo sapiens (Human) 
2025-12-18 | PXD063195 | Pride
T lymphoblasts Post-translational modifications Human Itraq Lc-ms/ms 
UnknownSerum DNA methylome of the colorectal cancer serrated pathway enables non-invasive detection.
Not available
S-EPMC11547225 | biostudies-literature
UnknownChromatin activity of IκBα mediates the exit from naive pluripotency.
Not available
S-EPMC12543326 | biostudies-literature
TranscriptomicsInfluence of Set7/9 on hESC differentiation
We analyzed the role of the histone lysine methyltransferase Set7/9 in the differentiation of human embryonic stem (ES) cells. Human ES cell lines expressing a control short hairpin and a short hairpin against Set7/9 were established and the genome wide expression profile was compared between both c...
ORGANISM(S): Homo sapiens 
2016-02-17 | E-GEOD-24768 | biostudies-arrayexpress
UnknownMeasuring performance on the Healthcare Access and Quality Index for 195 countries and territories and selected subnational locations: a systematic analysis from the Global Burden of Disease Study 2016.
Not available
S-EPMC5986687 | biostudies-literature
UnknownColombian surgical outcomes study insights on perioperative mortality rate, a main indicator of the lancet commission on global surgery - a prospective cohort study.
Not available
S-EPMC11382124 | biostudies-literature
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