Sort   by:  
 Page size 
TranscriptomicsRNAi profiling by array of human U-2-OS osteosarcoma cells with knockdown of Asf1a and Asf1b
We used RNAi to knock-down the two isoforms of Asf1, Asf1a and Asf1b, in human U-2-OS osteosarcoma cells. We obtained two replicates each with siRNAs against Asf1a, Asf1b, combined siRNAs against both isoforms, and two control samples. For these samples, we measured genome-wide transcription levels ...
ORGANISM(S): Homo sapiens 
2011-01-01 | E-MEXP-2671 | biostudies-arrayexpress
TranscriptomicsThe unique roles of DosT and DosS in DosR regulon induction and Mycobacterium tuberculosis dormancy
In Mycobacterium tuberculosis, the sensor kinases DosT and DosS activate the transcriptional regulator DosR, resulting in the induction of the DosR regulon, important for anaerobic survival and perhaps latent infection. The individual and collective roles of these sensors has been postulated biochem...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2009-06-26 | E-GEOD-16811 | biostudies-arrayexpress
UnknownFinding evolutionarily conserved cis-regulatory modules with a universal set of motifs.
Not available
S-EPMC2669485 | biostudies-literature
ProteomicsExploring the structural landscape of DNA maintenance proteins
Evolutionary annotation of genome maintenance (GM) proteins has conventionally been established by remote relationships within protein sequence databases. However, often no significant relationship can be established. Highly sensitive approaches to attain remote homologies based on iterative profile...
ORGANISM(S): Homo sapiens (Human) 
2024-10-17 | PXD043273 | Pride
Dna damage repair Protein folding Lc-ms/ms 
ProteomicsU2OS LC MSMS upon siRNA-eIF4A3 or 5nM ActD treatment.
Proteome analysis in U2OS cells treated with siRNA against eIf4A3 or 5nM Actinomycin D.
ORGANISM(S): Homo sapiens (Human) 
2021-09-08 | PXD016005 | Pride
U2os lc msms upon sirna-eif4a3 or 5nm actd treatment. 
TranscriptomicsNanopore RNA-seq of human cell lines treated with or without nicotinamide adenine dinucleotide (NAD+)
Investigation of transcriptome changes in four human cell lines (BJ, BJ-5ta, U2OS and HeLa) after treatment for 24 hours with nicotinamide adenine dinucleotide (NAD+). Cells were untreated as the control condition. Nanopore sequencing of cDNA was performed after library preparation with the ONT SQK...
ORGANISM(S): Homo sapiens 
2023-09-20 | E-MTAB-13187 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of JAK2wt and JAK2V617F+ iPSCs and iPSC-derived CD34+ progenitor-enriched cultures, either inflammatory cytokines treated or untreated.
PV-patient specific and control healthy individual-derived iPSCs were upon differentiation for 9 days into CD34+ hematopoietic progenitors treated with IFNγ, TNFα and TGFβ1 or untreated and used for transcriptome analysis. This dataset shows presence of cell-autonomous and strong non-cell autonomous...
ORGANISM(S): Homo sapiens 
2020-12-03 | E-MTAB-7693 | biostudies-arrayexpress
TranscriptomicsNanopore RNA-seq of human osteosarcoma cell line U2OS treated with siRNA against MDC1, PLRG1, or control siRNA with or without pladienolide B
The purpose was to investigate transcript and splicing changes in U2OS cells following siRNA-mediated depletion of MDC1 and PLRG1 or treatment with the splicing inhibitor pladienolide B. Cells were treated with control siRNA as control condition. Nanopore sequencing of cDNA was performed after libra...
ORGANISM(S): Homo sapiens 
2023-01-11 | E-MTAB-12497 | biostudies-arrayexpress
UnknownTargeting Ribosome Biogenesis in Cancer: Lessons Learned and Way Forward.
Not available
S-EPMC9100539 | biostudies-literature
UnknownThe Nucleolus: A Multiphase Condensate Balancing Ribosome Synthesis and Translational Capacity in Health, Aging and Ribosomopathies.
Not available
S-EPMC6721831 | biostudies-literature
Sort   by:  
 Page size