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ProteomicsER-shaping Atlastin proteins differentially contribute to flavivirus replication and assembly
Flaviviruses, including Dengue virus (DV) and Zika virus, extensively remodel the cellular endomembrane network to generate replication organelles that promote viral genome replication and virus production. However, it remains unclear how these membranes and associated cellular proteins act during t...
ORGANISM(S): Homo sapiens (Human) 
2019-10-17 | PXD014640 | Pride
Atl-2 Lfq A549 Proteome Atl-3 Calnexin Label-free Lc-ms/ms 
ProteomicsER-shaping Atlastin proteins differentially contribute to flavivirus replication and assembly
Flaviviruses, including Dengue virus (DV) and Zika virus, extensively remodel the cellular endomembrane network to generate replication organelles that promote viral genome replication and virus production. However, it remains unclear how these membranes and associated cellular proteins act during t...
ORGANISM(S): Homo sapiens (Human) 
2019-10-17 | PXD014639 | Pride
Atl-2 Atlastin Atl-3 Proteome Ap-lc-ms/ms 
ProteomicsPhosphatidic acid features double membrane vesicle formation during Hepatitis C and SARS-CoV-2 infection
Double membrane vesicles (DMVs) are used as replication organelles by pathogenic RNA viruses such as hepatitis C virus (HCV) and severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Viral DMVs are morphologically analogous to DMVs formed during autophagy, and although the proteins required...
ORGANISM(S): Homo sapiens (Human) 
2022-01-24 | PXD029692 | Pride
Dmvs Lipid phosphatidic acid Sars-cov-2 Hepatitis c 
ModelsMaier2022 - Stochastic Dynamics of Type I Interferon Responses
Maier2022 - Stochastic Dynamics of Type I Interferon Responses Our study aims to determine whether and how biochemical noise affects the information transduced in the JAK-STAT signaling pathway and investigate the transition between basal and activated state. To this end, we studied the stochastic ...
2022-10-25 | MODEL2210070001 | BioModels
UnknownIntegrative imaging reveals SARS-CoV-2 induced reshaping of subcellular morphology
Not available
EMPIAR-10490 | biostudies-other
Genomicsena-DATASET-DKFZ-IBIOS-01-06-2015-13:43:18:542-193 - samples
Whole Genome Sequencing of Huh7 cell lines
EGAD00001001386 | EGA
GenomicsEngineering of a promoterless anti-viral RNAi hairpin into an endogenous miRNA locus
Short hairpin RNA (shRNA) expression strategies that allow safe and persistent target mRNA knockdown are key to the success of many in vitro or in vivo RNAi applications. Here, we propose a novel solution which is expression of a promoterless miRNA-adapted shRNA (shmiRNA) from an engineered genomic ...
EGAS00001001252 | EGA
GenomicsBioinformatics of Data Analysis (B240)
Data Access Committee EGAC00001000346
EGAC00001000346 | EGA
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