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TranscriptomicsStarvation response in Drosophila and its implication for sex specific metabolism and aging
Background All animals must be able to adapt to changes in nutrient quality and supply. One striking aspect of this adaptive response is the extension of lifespan when caloric intake is reduced. These animals are also more resistant to various stresses, including starvation. We have characterized th...
ORGANISM(S): Drosophila melanogaster 
2010-06-05 | E-GEOD-1672 | biostudies-arrayexpress
TranscriptomicsMouse feeding experiment
Mice used in this study were 129/sv males, 8-15 weeks of age, which were housed individually and received water ad libitum. Normal fed animals were fed before and during the 48h experiment with standard food ad libitum. Sugar fed animals were fed before the experiment with standard food ad libitum a...
ORGANISM(S): Mus musculus 
2004-02-08 | E-GEOD-858 | biostudies-arrayexpress
TranscriptomicsIPC knockout, 14 day old female flies, 48h yeast feeding
Background Insulin signaling pathway is conserved from worms to humans. In Drosophila, three insulin-like peptides (dilps) are expressed in the insulin producing cells (IPCs) in the brain. In order to identify target genes of insulin signaling, the IPCs of female flies were destroyed during develop...
ORGANISM(S): Drosophila melanogaster 
2010-06-25 | E-GEOD-10625 | biostudies-arrayexpress
GenomicsBioinformatics of Data Analysis (B240)
Data Access Committee EGAC00001000346
EGAC00001000346 | EGA
Genomicsena-DATASET-DKFZ-IBIOS-12-04-2016-13:32:15:134-286 - samples
RNA sequencing data of whole blood samples from smoking and non-smoking mothers and their children at gestation/birth and follow-up years.
EGAD00001002011 | EGA
Genomicsena-DATASET-DKFZ-IBIOS-12-04-2016-13:35:10:904-287 - samples
ChIPseq data of whole blood samples from smoking and non-smoking mothers and their children at gestation/birth and follow-up years.
EGAD00001002012 | EGA
GenomicsDATA_SET_marlboro-EEP-2013-03-15 - samples
WGBS data of whole blood samples from smoking and non-smoking mothers and their children at gestation/birth and follow-up years.
EGAD00001000366 | EGA
GenomicsWhole genome bisufite sequencing of smoking and non-smoking mother-child pairsBisufite sequencing, RNA-seq and ChIP-Seq data of whole blood samples from smoking and non-smoking mothers and their children at gestation/birth and follow-up years.
Whole-blood samples of 16 mother-child pairs with differing maternal smoking behaviour were bisulfite treated and sequenced with deep coverage to identify smoking-associated differentially methylated regions. RNA-sequencing and ChIP-sequencing of 4 chromatin marks complete the data set and allow for...
EGAS00001000455 | EGA
GenomicsEngineering of a promoterless anti-viral RNAi hairpin into an endogenous miRNA locus
Short hairpin RNA (shRNA) expression strategies that allow safe and persistent target mRNA knockdown are key to the success of many in vitro or in vivo RNAi applications. Here, we propose a novel solution which is expression of a promoterless miRNA-adapted shRNA (shmiRNA) from an engineered genomic ...
EGAS00001001252 | EGA
Genomicsena-DATASET-DKFZ-HIPO-01-12-2017-13:02:22:609-63 - samples
This dataset contains paired fastq files for LMS tumor samples
EGAD00001003828 | EGA
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