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TranscriptomicsTranscriptome analysis of the archaeon Thermoplasma acidophilum cultured under aerobic and anaerobic conditions
Investigation of whole genome gene expression level changes in Thermoplasma acidophilum cultured under aerobic and anaerobic conditions. The analysis are further described in Na Sun, Cuiping Pan, Stephan Nickell, Matthias Mann, Wolfgang Baumeister, and István Nagy, Quantitative proteome and transcri...
ORGANISM(S): Thermoplasma acidophilum DSM 1728 
2011-09-26 | E-GEOD-21956 | biostudies-arrayexpress
UnknownUsing the Volta phase plate with defocus for cryo-EM single particle analysis.
Not available
S-EPMC5279940 | biostudies-literature
ProteomicsDirect visualization of ERAD nanocompartments within the cell
ER-associated degradation (ERAD) is an evolutionarily-conserved quality control mechanism where misfolded proteins are removed from the endoplasmic reticulum (ER) and degraded by the ubiquitin-proteasome system. While many ERAD-mediating proteins have been identified, it is unknown how they are spat...
ORGANISM(S): Chlamydomonas reinhardtii 
2020-05-26 | PXD009375 | Pride
Erad electron microscopy 
ProteomicsAutophagy preferentially degrades non-fibrillar polyQ aggregates
Aggregation of proteins containing expanded polyglutamine (polyQ) repeats is the cytopathologic hallmark of a group of dominantly inherited neurodegenerative diseases, including Huntington's disease (HD). Huntingtin (Htt), the disease protein of HD, forms amyloid-like fibrils by liquid-to-solid phas...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2026-10-23 | PXD044261 | Pride
Autophagosome Human hek293 Mouse neuro2a Poly-glutamine Huntingtin 
UnknownStructural and biochemical analysis of the sheath of Phormidium uncinatum.
Not available
S-EPMC107377 | biostudies-literature
ProteomicsTargeting the paralog encoded protein for degradation accounts for the opposite roles of NRBP1 and NRBP2 in regulating LINE1 retrotransposition
The activation of Long Interspersed Nuclear Element 1 (LINE1/L1) retrotransposons not only leads to genome instability, a factor associated with the development of human diseases, but also plays crucial biological roles in fostering genetic diversity and neuronal functions. Therefore, investigating ...
ORGANISM(S): Homo sapiens (Human) 
2025-06-07 | PXD051452 | Pride
Line1 Retrotransposon Nrbp2 Nrbp1 
UnknownPlant diversity influenced gross nitrogen mineralization, microbial ammonium consumption and gross inorganic N immobilization in a grassland experiment.
Not available
S-EPMC7406533 | biostudies-literature
GenomicsPQM-1 and Cobalt Chloride dependent gene expression changes in C. elegans
PQM-1 and Cobalt Chloride dependent gene expression changes in C. elegans
PRJNA580256 | ENA
ProteomicsIdentification of microtubule associated proteins
To find out the identities of microtubule-associated proteins whose abundances are visibly reduced in presence of Taxol. For this experiment, microtubule-associated proteins are pulleddown after treatment with Taxol. Untreated cells are used as a control.
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD035700 | Pride
Microtubule associated proteins  human  mitosis 
ProteomicsAn integrated workflow for cross-linking/mass spectrometry
We present a concise workflow to enhance the mass spectrometric detection of cross-linked peptides by introducing sequential digestion and the database search software Xi. We use sequential digestion to reduce the peptide size and increase identification rates. The methodology is independent of samp...
ORGANISM(S): Bos taurus (Bovine) Homo sapiens (Human) Gallus gallus (Chicken) Saccharomyces cerevisiae (Baker's yeast) Chaetomium thermophilum Equus caballus (Horse) 
2019-08-27 | PXD008550 | Pride
Xi Sequential digestion Cross-linking mass spectrometry 
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