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ProteomicsLFQ and SRM proteome analysis of Saliva reveals transition signatures from health to periodontal disease
Phase 1: The whole saliva samples were obtained from 66 systemically healthy subjects consisting of patients with chronic periodontitis (CP), generalized aggressive periodontitis (G-AgP), gingivitis and individuals with periodontal health. The use of humans for study satisfied the requirements of th...
ORGANISM(S): Homo sapiens (Human) 
2018-04-10 | PXD007535 | Pride
Data integration Lfq Srm Lc-ms/ms 
UnknownTREM-1 Is Upregulated in Experimental Periodontitis, and Its Blockade Inhibits IL-17A and RANKL Expression and Suppresses Bone loss.
Not available
S-EPMC6832657 | biostudies-literature
ProteomicsProteome mapping of human gingival tissue in health and disease
Gingival tissue proteome is at the forefront of the periodontal research, yet have been hampered by lack of sufficient tissue-extraction methods. Using an emerging technology for tissue homogenization, pressure cycling technology (PCT), we characterize the gingival tissue proteomic profiles of both ...
ORGANISM(S): Homo sapiens (Human) 
2020-09-25 | PXD018029 | Pride
Pressure cycling technology Gingival tissue proteome Chronic periodontitis 
UnknownNovel and known periodontal pathogens residing in gingival crevicular fluid are associated with rheumatoid arthritis.
Not available
S-EPMC8048861 | biostudies-literature
UnknownSaliva Versus All-Site Microbiome and Proteome Mapping in Periodontitis.
Not available
S-EPMC12531364 | biostudies-literature
UnknownProteome and Microbiome Mapping of Human Gingival Tissue in Health and Disease.
Not available
S-EPMC7566166 | biostudies-literature
UnknownTargeted Proteomics Guided by Label-free Quantitative Proteome Analysis in Saliva Reveal Transition Signatures from Health to Periodontal Disease.
Not available
S-EPMC6030726 | biostudies-literature
UnknownDysbiosis of the Oral Ecosystem in Severe Congenital Neutropenia Patients.
Not available
S-EPMC7317524 | biostudies-literature
ProteomicsHistone-like family of nucleoid structuring protein of A. actinomycetemcomitans promotes biofilm formation and alters protein dynamics of other species within multi-species biofilm
Aggregatibacter actinomycetemcomitans is a Gram-negative organism, strongly associated with aggressive forms of periodontitis. An important virulence property of A. actinomycetemcomitans is its ability to form tenacious biofilms that can attach to abiotic as well as biotic surfaces. The histone-like...
ORGANISM(S): Candida albicans (Yeast) Aggregatibacter aphrophilus Streptococcus mutans Streptococcus oralis Aggregatibacter actinomycetemcomitans (Actinobacillus actinomycetemcomitans) (Haemophilus actinomycetemcomitans) Fusobacterium nucleatum Veillonella dispar Actinomyces oris 
2018-06-05 | PXD008444 | Pride
Multi-species biofilm Hns A. actinomycetemcomitans Label-free quantification 
ProteomicsComparative Proteomic Signatures in Periodontitis: Saliva, Gingival Crevicular Fluid (GCF), Plaque, vs. Serum
Saliva, gingival crevicular fluid (GCF), and serum are common sources for studying host response and oral microbiota in periodontal patients. This cross-sectional study aimed to compare the proteomic signatures of periodontitis patients using full-mouth periodontal sampling with those obtained from...
ORGANISM(S): Homo sapiens (Human) 
2025-10-27 | PXD055509 | Pride
Gcf Serum Saliva Periodontitis 
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