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UnknownMonitoring of Nutrients, Metabolites, IgG Titer, and Cell Densities in 10 L Bioreactors Using Raman Spectroscopy and PLS Regression Models.
Not available
S-EPMC12030344 | biostudies-literature
ProteomicsNelfinavir overcomes proteasome inhibitor resistance in multiple myeloma by modulating lipid bilayer composition and fluidity
Nelfinavir has broad anti-cancer activity precilincally as a single agent and in combination. Clinically, it is particularly effective in the therapy of proteasome inhibitor-refractory multiple myeloma. The broad anti-cancer mechanism of action of nelfinavir implies that it may interfere with very f...
ORGANISM(S): Homo sapiens (Human) 
2021-11-02 | PXD023260 | Pride
Proteasome inhibitors Affinity-purification Upr Crispr/cas9 Adipor2 Ezetimibe Nelfinavir Hiv-protease inhibitor Multiple myeloma 
TranscriptomicsResponse of Lactococcus lactis to different growth rates
The development of transcriptomic tools has allowed exhaustive description of stress responses. These responses always superimpose a general response associated to growth rate decrease and a specific one corresponding to the stress. The exclusive growth rate response can be achieved through chemosta...
ORGANISM(S): Lactococcus lactis 
2010-06-25 | E-GEOD-10256 | biostudies-arrayexpress
TranscriptomicsLactococcus lactis stringent response
The stringent response was defined in Lactococcus lactis through transcript profiling after the addition of a chemical inductor, the norvaline. Gene expression was measured in the exponential growth phase (reference sample) and at 1.6 h after norvaline addition. Four hundred and sixty one differenti...
ORGANISM(S): Lactococcus lactis 
2010-06-25 | E-GEOD-10254 | biostudies-arrayexpress
UnknownAssessment of diffusion-weighted MRI in predicting response to neoadjuvant chemotherapy in breast cancer patients.
Not available
S-EPMC9837175 | biostudies-literature
TranscriptomicsIn vivo gene expression in granulosa cells during pig terminal follicular development.
The aim of this study is the identification of genes and gene networks involved in pig ovarian follicular development. cDNA nylon micro-arrays (2849 sequenced clones) were designed from different libraries : four subtractive suppressive hybridization libraries (generated from small versus large and ...
ORGANISM(S): Sus scrofa 
2008-04-30 | E-GEOD-5798 | biostudies-arrayexpress
TranscriptomicsProgressive loss of PGC-1alpha expression in aging muscle potentiates glucose intolerance and systemic inflammation
Decreased mitochondrial mass and function in muscle of diabetic patients is associated with low PGC-1alpha, a transcriptional coactivator of the mitochondrial gene program. To investigate whether reduced PGC-1alpha and oxidative capacity in muscle directly contributes to age-related glucose intolera...
ORGANISM(S): Mus musculus 
2013-12-05 | E-GEOD-52550 | biostudies-arrayexpress
UnknownThe significance of refuge heterogeneity for lowland stream caddisfly larvae to escape from drift.
Not available
S-EPMC6375960 | biostudies-literature
UnknownLoss-of-function mutations in ISCA2 disrupt 4Fe-4S cluster machinery and cause a fatal leukodystrophy with hyperglycinemia and mtDNA depletion.
Not available
S-EPMC5839994 | biostudies-literature
TranscriptomicsIn vivo gene expression in granulosa cells during pig terminal follicular development- oligo
These vector oligonucleotide hybridizations were performed to determine the quality of the spotting process. EST with low signal values of the vector array were excluded from the analysis, since they probably were mis-amplified or mis-spotted Keywords: spotting control cDNA arrays (GPL3978) were fi...
ORGANISM(S): Sus scrofa 
2008-04-30 | E-GEOD-5797 | biostudies-arrayexpress
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