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ProteomicsAfrican Penguin (Spheniscus demersus) Plasma Samples
Fractionation of normal and abnormal African penguin samples via capillary electrophoresis demonstrated a change from a left skewed composition to a right skewed composition. Further analysis of this fraction via mass spectrometry revealed key proteins associated with this skewed.
ORGANISM(S): Spheniscus demersus 
2021-09-09 | PXD018096 | Pride
Ce African penguin Lc-ms Plasma 
ProteomicsGrowth cone-enriched proteome of embryonic to early postnatal mouse brain
A growth cone (GC) is a part of a neuron considered a hub for axon growth, motility and guidance functions. Here, we present a dataset on the protein profiling of the growth cone-enriched fractions derived from E18, P0, P3, P6 and P9 C57BL/6J mouse pups. For comparison, we analyzed non-growth cone m...
ORGANISM(S): Mus musculus (Mouse) 
2019-05-03 | PXD012134 | Pride
Growth cone Sucrose gradient ultracentrifugation Mouse brain 
ProteomicsLabeled quantitative proteomics dataset of optogenetics induced axon regeneration
This labeled quantitative proteomics dataset was collected from a transgenic channel rhodopsin mouse model (Chr2) subjected to light stimulation after traumatic optic nerve crush (ONC) was performed. Mouse models expressing channel rhodopsin were subjected to therapeutic light stimulation promoting ...
ORGANISM(S): Mus musculus (Mouse) 
2022-08-12 | PXD032788 | Pride
Rhythmic light stimulation Quantitative proteome Axon regeneration Optogenetic stimulation 
ProteomicsMyelin basic protein phospholipid complexation likely competes with deimination in experimental autoimmune encephalomyelitis mouse model
Analysis of deimination of MBP in the precence of different phospholipid classes
ORGANISM(S): Bos taurus (Bovine) 
2021-09-08 | PXD015494 | Pride
Lc-ms Mbp 
ProteomicsQuantitative proteomic analysis after neuroprotective MyD88 inhibition in the retinal degeneration 10 mouse
Progressive dysfunction and death of photoreceptors occurs in blinding diseases such as age-related macular degeneration and retinitis pigmentosa. The MyD88 protein is a central adaptor molecule for innate immune system Toll-like receptors (TLR) and interleukin-1 receptor (IL-1R), which are active i...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-17 | PXD024501 | Pride
Retinal degeneration Proteomics Photoreceptors Crystallin Toll-like receptors Myd88 Itraq 
ProteomicsQuantitative Proteomic Analysis of C57BL/6J mice after optic nerve crush Using iTRAQ Labeling
We used two groups of C57BL/6J mice, one with optic nerve crush on one eye, and another with no crush as control. Three mice were subjected to optic nerve crush, with sample names 121, 113, 114 and two were used as control with sample names 118 and 119. For the optic nerve crush, a surgical peritomy...
ORGANISM(S): Mus musculus (Mouse) 
2020-05-26 | PXD016197 | Pride
Nerve crush Optic nerve Itraq 
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