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Proteomics and phosphoproteomics of mouse bilateral striatum
ORGANISM(S): Mus musculus (Mouse) 
2025-10-06 | PXD056740 | Pride
Disrupted-in-schizophrenia 1 (DISC1) is a key protein involved in behavioral processes and various mental disorders, including schizophrenia and major depression. A transgenic rat modestly overexpressing non-mutant human DISC1, modeling aberrant proteostasis of the DISC1 protein, displays behavioral...
ORGANISM(S): Homo sapiens (Human) Rattus norvegicus (Rat) 
2018-02-27 | PXD008123 | Pride
Gamma knife surgery (GKS) is used for treatment of various brain disorders. The effects of gamma irradiation to targeted and un-targeted regions were evaluated by monitoring gene expression changes in the unilateral irradiated (60 Gy) and contralateral un-irradiated striata in the rat. Striata of ir...
ORGANISM(S): Rattus norvegicus 
2008-10-18 | GSE13220 | GEO
Transcriptomics of Rat Striata 16 h after Gamma Knife Surgery: Distinct Bilateral Effects in the Un-irradiated Striatum
ChI-D2RKO mice showed an altered transcriptomic profile in the dorsomedial striatum in response to contingent cocaine administration. In particular, the expression of critical cocaine-induced transcription factors was not activated in the mutants. This evidence suggests that the altered transcriptio...
ORGANISM(S): Mus musculus 
Vascular cognitive impairment (VCI) is a major cause of dementia, characterized by cognitive dysfunction resulting from cerebrovascular disease. Chronic cerebral hypoperfusion (CCH) is a significant contributor to VCI, impacting regions such as the white matter and the hippocampus. Despite the known...
ORGANISM(S): Mus musculus 
2025-01-08 | GSE275195 | GEO
Vascular cognitive impairment (VCI) is a major cause of dementia, characterized by cognitive dysfunction resulting from cerebrovascular disease. Chronic cerebral hypoperfusion (CCH) is a significant contributor to VCI, impacting regions such as the white matter and the hippocampus. Despite the known...
ORGANISM(S): Mus musculus 
2025-01-08 | GSE275194 | GEO
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