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ProteomicsiCAB: Development of an in situ cell-type specific proteome analysis method using antibody-mediated biotinylation
Since proteins are essential molecules exerting cellular functions, decoding proteome changes is the key to understanding the normal physiology and pathogenesis mechanism of various diseases. However, conventional proteomic studies are often conducted on tissue lumps, in which multiple cell types ar...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-12 | PXD046362 | Pride
Neuron Astrocytes Microglia. Brain Mass spectrometry Cell-type-specific proteome analysis Immunohistochemistry Biotin-tyramide 
TranscriptomicsComparison between Saccharomyces cerevisiae HS 10, HS 34 and HS 12, HS 37
Gene expression of different flocculent (HS 10 and HS 34) and powdery (HS 12 and HS 37) yeast strains compared to each other during exponential and stationary growth phase was analysed. The isolation of RNA was done by disruption of the cells under liquid nitrogen using mortar and pistil and then th...
ORGANISM(S): Saccharomyces cerevisiae 
2008-12-11 | E-GEOD-12369 | biostudies-arrayexpress
TranscriptomicsSaccharomyces cerevisiae sorted and untreated
Gene expression of a vital, stained and sorted subpopulation of Saccharomyces cerevisiae with high affinity to glucose, harvested at a dilution rate of D=0.160 h-1, and of cells from the whole population without further treatment grown at the same dilution rate were analysed. The isolation of RNA wa...
ORGANISM(S): Saccharomyces cerevisiae 
2007-10-01 | E-GEOD-8247 | biostudies-arrayexpress
ProteomicsAscorbate peroxidase (APEX2) -mediated proximity-based proteomics for HTT protein interactions
Huntington’s Disease (HD), a progressive neurodegenerative disorder with no disease-modifying therapies, is caused by a CAG repeat expansion in the HD gene encoding polyglutamine-expanded huntingtin (HTT) protein. Mechanisms of HD cellular pathogenesis and cellular functions of the normal and mutan...
ORGANISM(S): Homo sapiens (Human) 
2026-03-16 | PXD059663 | Pride
Huntington’s disease Protein interactions Huntingtin Dna damage Neurodegeneration 
ProteomicsDetection of Cell-Cell Interactions via Photocatalytic Cell Tagging
The growing appreciation of immune cell-cell interactions within disease environments has led to significant efforts to develop highly effective protein- and cell-based immunotherapies. However, characterizing these complex cell-cell interfaces in high resolution remains challenging. Thus, technol...
ORGANISM(S): Bos taurus (Bovine) Oryctolagus cuniculus (Rabbit) Gallus gallus (Chicken) 
2022-06-03 | PXD032203 | Pride
Flavin-based photocatalysis Phenoxy radical generation Tyrosine labeling 
UnknownProtocol for tyramide signal amplification immunohistochemical detection of Notch1 signaling in the vascular system.
Not available
S-EPMC11683232 | biostudies-literature
UnknownIdentification of lectin counter-receptors on cell membranes by proximity labeling.
Not available
S-EPMC5881670 | biostudies-literature
ProteomicsAPEX2 and TurboID Define Unique Subcellular Proteomes
Proximity labeling has emerged as a prominent, reliable tool for obtaining local proteomes from a wide range of cell-types. Two major classes of labeling reagents, peroxidase based (APEX family), or biotin-ligase based (BioID family) have been developed in parallel. These two approaches are often us...
ORGANISM(S): Homo sapiens (Human) 
2025-12-15 | PXD068036 | Pride
Proteomics Apex Cellular compartments Turboid Proximity labeling 
ProteomicsA novel multispecies peptide for brain delivery of nanoscale payloads.
This dataset contains LC MS/MS proteomics data from a cell surface proximity labeling experiment designed to identify proteins near the BBB-penetrating peptide Cerepep (CP). WT GBM cells were treated with a CP HRP complex (with biotin blocked HRP as control), followed by tyramide biotinylation, stre...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2026-01-30 | MSV000100657 | MassIVE
ProteomicsAssays using HRP-expressed pseudovirus for virus receptor identification (biotin-tyramide)
In several virus infection, the host membrane proteins involved in virus attachment to host cells are important target for researchers. We are now using proximity labeling strategy to identify them.
ORGANISM(S): Homo Sapiens (human) 
2026-04-06 | PXD075131 | JPOST Repository
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