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UnknownPeripapillary atrophy in patients with birdshot chorioretinitis.
Not available
S-EPMC12320589 | biostudies-literature
ProteomicsERAP2 Increases the Abundance of a Peptide Submotif Highly Selective for the Birdshot Uveitis-Associated HLA-A29
Birdshot Uveitis (BU) is a blinding inflammatory eye condition that only affects HLA-A29-positive individuals. Genetic association studies linked ERAP2 with BU, an aminopeptidase which trims peptides before their presentation by HLA class I at the cell surface, which suggests that ERAP2-dependent pe...
ORGANISM(S): Homo sapiens (Human) 
2021-09-10 | PXD024109 | Pride
Hla-a29 Birdshot Erap2 Autoimmunity Immunopeptidome 
UnknownBirdshot chorioretinopathy: current knowledge and new concepts in pathophysiology, diagnosis, monitoring and treatment.
Not available
S-EPMC4866419 | biostudies-literature
ProteomicsAllele-specific alterations in the peptidome underlie the joint association of HLA-A*29:02 and Endoplasmic Reticulum Aminopeptidase 2 (ERAP2) with Birdshot Chorioretinopathy
Birdshot chorioretinopathy (BSCR) is a rare inflammatory eye disease very strongly associated with HLA-A*29:02, with >95% of patients carrying this allele. BSCR is also associated with endoplasmic reticulum aminopeptidase (ERAP)2, an enzyme involved in processing HLA class I ligands. We analyzed the...
ORGANISM(S): Homo sapiens (Human) 
2018-05-17 | PXD007679 | Pride
Hla-a*29:02 Endoplasmic reticulum aminopeptidase 2 (erap2) Birdshot chorioretinopathy 
UnknownFunctionally distinct ERAP1 and ERAP2 are a hallmark of HLA-A29-(Birdshot) Uveitis.
Not available
S-EPMC6276832 | biostudies-literature
UnknownHLA-A29 and Birdshot Uveitis: Further Down the Rabbit Hole.
Not available
S-EPMC7687429 | biostudies-literature
UnknownSingle-cell profiling identifies a CD8bright CD244bright Natural Killer cell subset that reflects disease activity in HLA-A29-positive birdshot chorioretinopathy.
Not available
S-EPMC11291632 | biostudies-literature
UnknownLong-Term Outcomes of Birdshot Chorioretinopathy Treated with Corticosteroids: A Case Reports.
Not available
S-EPMC10455668 | biostudies-literature
UnknownOptic Disc Edema Is an Under-Recognized Feature of Birdshot Chorioretinitis.
Not available
S-EPMC11567670 | biostudies-literature
UnknownMicrovascular and Structural Characterization of Birdshot Chorioretinitis in Active and Inactive Phases.
Not available
S-EPMC11505013 | biostudies-literature
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