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ProteomicsPediatric burn blister fluid LC-MS/MS SWATH
Blister fluid (BF) is a novel and viable research matrix for burn injury study, which can reflect both systemic and local micro-environmental responses. The protein abundance in BF from different burn severities were initially observed using a 2D SDS-PAGE approach. Subsequently, a quantitative data ...
ORGANISM(S): Homo sapiens (Human) 
2018-12-21 | PXD011102 | Pride
Proteomics Swath Blister fluid Time to re-epithelialization Burn injury Burn depth 
ProteomicsProteome of paediatric burn wound fluid collected via negative pressure wound therapy
Negative pressure wound therapy (NPWT) has been used to promote wound healing in a variety of settings, including as an adjunct to silver-impregnated dressings in the acute management of paediatric burns. Fluid aspirated by the NPWT system represents a potentially insightful research matrix for unde...
ORGANISM(S): Homo sapiens (Human) 
2022-08-15 | PXD023161 | Pride
Exudate Proteomics Swath Paediatric Effluent Npwt Oedema fluid Burn Blister fluid Lc-ms/ms 
ProteomicsProteome of paediatric burn wound fluid collected via negative pressure wound therapy
Negative pressure wound therapy (NPWT) has been used to promote wound healing in a variety of settings, including as an adjunct to silver-impregnated dressings in the acute management of paediatric burns. Fluid aspirated by the NPWT system represents a potentially insightful research matrix for unde...
ORGANISM(S): Homo sapiens (Human) 
2021-01-04 | PXD023168 | Pride
Exudate Proteomics Swath Paediatric Effluent Npwt Oedema fluid Burn Blister fluid Lc-ms/ms 
ProteomicsInflammatory proteins and neutrophil extracellular traps increase in burn blister fluid after 24 hours post-burn
Burn wound blister fluid is a valuable matrix for understanding the biological pathways associated with burn injury. In this study, 152 blister fluid samples collected from paediatric burn wounds at two different hospitals were analysed using mass spectrometry proteomic techniques. The protein abund...
ORGANISM(S): Homo sapiens (Human) 
2024-03-04 | PXD050003 | Pride
Proteomics Child Wound fluid Paediatric Swath Lcms Burn 
TranscriptomicsMultiomic single-cell sequencing of skin and blister fluid from patients with severe cutaneous adverse drug reactions.
Severe cutaneous adverse reactions (SCAR) are rare but life-threatening drug reactions mediated by human leukocyte antigen (HLA) class I-restricted CD8+ T-cells. To obtain an unbiased assessment of SCAR cellular immunopathogenesis, we performed single-cell (sc) transcriptome, surface proteome, and T...
ORGANISM(S): Homo sapiens 
2026-08-14 | GSE275871 | GEO
TranscriptomicsSingle-cell RNAseq identifies clonally expanded antigen-specific T-cells following intradermal injection of gold nanoparticles loaded with diabetes autoantigen in humans
Gold nanoparticles (GNPs) have been used in the development of novel therapies as a way of delivery of both stimulatory and tolerogenic peptide cargoes. Here we report that intradermal injection of GNPs loaded with the proinsulin peptide C19-A3, in patients with type 1 diabetes, results in recruitme...
ORGANISM(S): Homo sapiens 
2023-10-06 | E-MTAB-13388 | biostudies-arrayexpress
UnknownMass spectrometry based data of the blister fluid proteome of paediatric burn patients.
Not available
S-EPMC4976667 | biostudies-literature
UnknownPilot study investigating BP-180 in extracellular vesicles derived from blister fluid of bullous pemphigoid patients.
Not available
S-EPMC10338600 | biostudies-literature
ProteomicsEarly clinical and biomarker responses after treatment in patients with non-segmental vitiligo.
This study was a prospective cohort study in patients with non-segmental vitiligo receiving SoCtreatment. Standard of care treatment involved a potent topical corticosteroid, such as Fluticasonepropionate (FP) cream, used alone or in combination with NB-UVB phototherapy treatment, based ondisease se...
ORGANISM(S): Homo sapiens (Human) 
2026-05-19 | PAD000045 | Pride
ProteomicsRole of sEH inhibition in immune function in humans (blister fluid)
Humans were dosed with vehicle or an sEH inhibitor and injected with bacterial PAMPs to induce a skin blisters. Skin blister fluid was analyzed by LCMS for a targeted panel of eicosanoids
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2025-10-02 | MSV000099360 | MassIVE
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